2011 Cardiac Arrhythmia Mechanisms Gordon Research Conference

描述(申请人提供)：心律失常是发达国家死亡率和发病率的主要原因。然而，致命性心律失常的机制仍有待阐明。本次戈登研究会议每年举行两次，主要目的是探索包括房颤和室颤在内的最复杂心律失常的基本机制。诊断、治疗和预防心律失常的新方法将需要使用高度复杂的工具，这些工具结合了多种技术，包括新的成像模式、遗传学、分子和结构生物学、组织工程、免疫化学、膜片钳、电波传播的光学和高密度电极标测以及计算机建模。该领域的代表是分子生物学、细胞电生理学、生物物理学、生物医学工程、数学生物学、系统生物学和临床心脏病学研究前沿的杰出研究人员和专家。本次会议提供了一个论坛，就多种因素在复杂心律失常和心脏性猝死的机制中的作用进行互动和分享想法，以期达到开发新疗法的目标。

DESCRIPTION (provided by applicant): Cardiac arrhythmias are a major cause of mortality and morbidity in the developed world. Yet, the mechanisms of deadly arrhythmias remain to be elucidated. The main goal of this biannual Gordon Research Conference is to explore the fundamental mechanisms of the most complex arrhythmias, including atrial and ventricular fibrillation. New approaches to diagnosis, treatment, and prevention of cardiac arrhythmias will require the use of highly sophisticated tools that combine multiple technologies including novel imaging modalities, genetics, molecular and structural biology, tissue engineering, immunochemistry, patch-clamping, optical and high density electrode mapping of electrical wave propagation, and computer modeling. This field is represented by outstanding investigators at the forefront of research and experts in molecular biology, cellular electrophysiology, biophysics, biomedical engineering, mathematical biology, systems biology and clinical cardiology. This conference provides a forum to interact and share ideas about the role of numerous factors in the mechanisms of complex cardiac arrhythmias and sudden cardiac death, towards the goal of developing novel therapeutics.