HPV Vaccine Education Intervention for Medically Underserved High-risk Population

描述（由申请人提供）：本研究的长期目标是发展和评估一种多文化、多语言的健康素养干预措施，以促进对HPV疫苗的了解，并在青春期前女孩的父母和HPV感染高风险的青春期女孩中促进知情的HPV免疫接种决策。本研究关注的人群包括韩国人、越南人、菲律宾人、非裔美国人和拉丁美洲人。本研究的具体目的是：(1)确定不同高危人群的HPV疫苗素养水平、态度、认知和信息来源；(2)确定干预措施的具体主题、信息要素和沟通策略，以增强患者对疫苗风险和益处的理解和评估；(3)确定影响对HPV疫苗信息的关注、理解和评估的文化价值观、信仰和做法，旨在为免疫决策提供信息。(4)设计和制作一个多元文化、多语言的教育干预，为HPV感染高风险的不同人群量身定制关于HPV疫苗接种的认知可及性、文化胜任性、健康素养信息；(5)评估使用下一代数字视频光盘技术的交互式多元文化、多语言学习和决策工具的功效，以增加患者对HPV疫苗的了解。评估HPV疫苗接种的风险和益处，并在本研究中促进不同种族/民族群体的知情疫苗接种决策。这项研究响应了卫生与公众服务部消除种族和族裔健康差距的倡议，该倡议呼吁人们注意在获得预防性保健资源方面的差距，主要是少数种族和族裔之间的差距。这项研究将进行焦点小组和认知访谈，以指导以四种不同的语言（英语、西班牙语、韩语和越南语）为16个不同的受众量身定制的具有文化能力的、适合年龄的材料的开发，并将其保存在一张蓝光光盘上。它将对决策量表进行跨文化验证，以用于我们的五个研究人群。它还将在五个研究人群中对卫生素养干预措施进行随机对照疗效评估。该研究寻求来自每个种族/民族社区的成熟的、受人尊敬的社区组织的合作，以指导研究，并为各自社区的潜在研究参与者提供机会。它还利用我们在复杂、多文化、多语言研究方面的丰富经验，有效地管理这项多受众健康素养研究的挑战。

DESCRIPTION (provided by applicant): The long-term goal of this study is to develop and evaluate a multicultural, multilingual health literacy intervention to promote knowledge about the HPV vaccine and foster informed HPV immunization decisions among parents of preadolescent girls and among adolescent girls at high risk for HPV infection. The populations of interest in this study are Koreans, Vietnamese, Filipinos, African Americans and Latinos. The specific aims of this study are to: (1) identify HPV vaccine literacy levels, attitudes, perceptions and information sources among diverse at-risk populations, (2) identify specific themes, message elements and communication strategies for an intervention that enhances patient comprehension and evaluation of the risks and benefits of the vaccine, (3) identify cultural values, beliefs, and practices that influence attention, comprehension, and appraisal of HPV vaccine information intended to inform an immunization decision, (4) design and produce a multicultural, multilingual education intervention that delivers cognitively accessible, culturally competent, health literacy information about HPV vaccination tailored to diverse populations at high risk for HPV infection, and (5) evaluate the efficacy of an interactive multicultural, multilingual learning and decision tol using next-generation digital videodisc technology to increase patients' knowledge about the HPV vaccine, assess the risks and benefits attendant to HPV vaccination, and promote informed vaccination decisions among the diverse racial/ethnic groups in this study. This study responds to the HHS Initiative to Eliminate Racial and Ethnic Health Disparities, which cals atention to the gaps in access to preventive health resources, principally among racial and ethnic minorities. This study will conduct focus groups and cognitive interviews to guide development of culturally competent, age-appropriate materials tailored to 16 diverse audiences in four different languages (English, Spanish, Korean and Vietnamese) on a single Blu-ray disc. It will conduct cross-cultural validation of decision-making scales for use with our five study populations. It will also conduct a randomized, controlled efficacy evaluation of the health literacy intervention among the five study populations. The study enlists the collaboration of established, well-regarded community-based organizations from each of the racial/ethnic communities to guide the study and provide access to prospective study participants in their respective communities. It also leverages our extensive experience with complex, multicultural, multilingual studies to effectively manage the challenges of this multi-audience health literacy study. PUBLIC HEALTH RELEVANCE: This health literacy study addresses the need for multilingual, multicultural, HPV vaccine education materials to empower individuals at high risk for HPV infection to make an informed immunization decision, which offers a significant public health benefit.