Network Chair for the Pacific Northwest DPBRN

描述(由申请人提供)：我们建议建立太平洋西北牙科实践基础研究网络(PNW/DPBRN)，并在本申请中设立网络主席办公室。此网络教席申请是华盛顿大学和俄勒冈卫生与科学大学牙科学院合作提交的。首席研究员是蒂莫西·A·德鲁恩博士，他是华盛顿大学负责研究和学术事务的执行副院长和生物统计学和牙科公共卫生科学教授，因此华盛顿大学是申请机构。OHSU的副主任是Jack Ferracane博士，OHSU修复牙科教授和主席，OHSU是一家分包机构。主要的临床合作研究人员是密歇根大学的乔尔·伯格(Joel Berg)和俄亥俄州立大学的托马斯·希尔顿(Thomas Hilton)。PNW网络计划覆盖华盛顿州、俄勒冈州、爱达荷州、蒙大拿州和犹他州这五个州。这项拟议的团队工作成功的可能性取决于团队在关键领域非常相关的先前经验，包括DeRouen博士在NIDCR资助的多中心临床试验中担任私人助理的经验以及在临床牙科研究中开发模型培训计划的经验，Berg博士在行业赞助的临床试验中招募和监督临床医生的经验，以及Ferracane和Hilton博士在俄勒冈州和华盛顿州西南部建立口腔健康研究实践网络的经验。一个重要的合作者是Delta Dental，数据分析中心，通过它可以获得基于Delta Dental在五个州网络地区的保险索赔的试点和观察性研究的数据。提议建立一个共同监督该行动的组织结构，其中包括使用分布在这一大片地理区域的五名区域协调员。提出了一项积极招募网络从业者的战略，包括与各州牙科协会、牙科校友协会合作，特别是与当地牙科学习俱乐部合作。将为参与者提供一个基于非常成功的临床牙科研究方法暑期研究所的教育计划。除了RFA授权的执行委员会和协议审查委员会以及DSMB之外，还提议设立一个出版物委员会、一个牙科保险联络委员会和一个外部咨询委员会，以促进该网络的运作。这个应用程序与一个应用程序配对成为数据协调中心，该中心也来自华盛顿大学，私人侦探布赖恩·勒鲁博士和生物识别核心的其他成员共同调查。鉴于德鲁恩博士之前开发生物测量核心的历史，网络主席和协调中心之间的密切合作和协调是有保证的。

DESCRIPTION (provided by applicant): We propose to establish the Pacific Northwest Dental Practice Based Research Network (PNW/DPBRN), and to create the Office of the Network Chair in this application. This Network Chair application is submitted as a collaborative effort between the University of Washington and Oregon Health and Science University Schools of Dentistry. Principal Investigator is Timothy A. DeRouen, Ph.D., Executive Associate Dean for Research and Academic Affairs and Professor of Biostatistics and Dental Public Health Sciences at UW, so the University of Washington is the applicant institution. Co-P.I. is Jack Ferracane, Ph.D., Professor and Chairman of Restorative Dentistry at OHSU, with OHSU as a subcontracting institution. Key clinical co-investigators are Joel Berg, DDS, MS, of UW and Thomas Hilton, DMD, MS of OHSU. The PNW network is proposed for the five state area of Washington, Oregon, Idaho, Montana, and Utah. The likelihood of success of this proposed team effort is predicated on the very relevant prior experience of the team in crucial areas, including Dr. DeRouen's experience as P.I. on an NIDCR-funded multicenter clinical trial and in developing model training programs jn clinical dental research, Dr. Berg's experience in recruiting and overseeing clinicians in industry-sponsored clinical trials, and the experience of Drs. Ferracane and Hilton in developing a Practice-based Research in Oral Health network of dentists in Oregon and Southwest Washington. An important collaborator is the Delta Dental,Data Analysis Center, through which data for pilot and observational studies based on Delta Dental insurance claims in the five state network region can be obtained. An organizational structure is proposed for shared oversight of the operation which includes the use of five regional coordinators spread across this large geographical region. An aggressive strategy of recruitment of Network practitioners is proposed that includes working with state dental associations, dental alumni associations, and especially with local dental study clubs. An educational program for participants will be offered that is based on the highly successful Summer Institute in Clinical Dental Research Methods. Besides the Executive and Protocol Review Committees and DSMB mandated by the RFA, also proposed to facilitate the operations of the Network are a Publications Committee, a Dental Insurance Liaison Committee, and an External Advisory Committee. This application is paired with one to become the Data Coordinating Center, also from the University of Washington, with Brian Leroux, Ph.D. as P.I. and other members of the Biometry Core as co-investigators. Given Dr. DeRouen's previous history in developing the Biometry Core, close collaboration and coordination between Network Chair and Coordinating Center is.assured.