Michigan Institute for Clinical and Health Research (MCHR)

2007年，CTSA向密歇根临床与健康研究所（MICHR）提供的资金标志着密歇根大学（UM）临床转化研究（CTR）转型的开始。这个奖项，加上强大的机构支持和不断增长的教师参与，使UM从一个主要的基础科学研究机构发展成为一个拥有全面研究组合的机构。实现这一目标的基础是：整合和创新的培训和教育计划，已触及近2000名学员和教职员工；集中和优化先前分散的研究服务，为用户创造创新机会；拨款1020万美元用于加速创新的试点研究；以及研究人员与社区和CTSA全国联盟的新伙伴关系的参与。在续期期间，CTSA资金与强大的机构支持将使MICHR能够实现5个总体目标：1)优化培训和指导，以创建下一代研究团队和临床和转化研究人员；2)增加基础设施和完善研究服务，以减少整个转化研究连续体的障碍并最大限度地提高研究生产力；3)促进合作，利用创新方法和技术促进发现；4)加强以社区和实践为基础的伙伴关系，以确保双向学习、研究和实施有利于健康的研究成果；5)积极领导和参与全国CTSA联盟活动，并参与跨CTSA合作。这些目标将通过以下方式实现：将教育扩展到新的领域，以加强CTR调查员的储备，并部署更灵活的培训工具；加强现有服务并推出新服务，以影响开办学习的时间和招聘；利用主要的资讯科技投资，将CTR研究人员的需求完全整合到资讯科技领域；利用新的基于实践的研究网络；扩展评估以有效地评估和优化我们的绩效。MICHR将成为进行高质量、高影响力临床和转化研究的改进和创新的引擎，以促进密歇根州和全国的健康。

The CTSA funding to the Michigan Institute for Clinical and Health Research (MICHR) in 2007 marked the beginning of a transformation of clinical-translational research (CTR) at the University of Michigan (UM). This award, coupled with strong institutional support and growing faculty engagement, enabled UM to evolve from a predominantly basic science research institution to one with a comprehensive research portfolio. This has been achieved on the foundation of: integrated and innovative training and educational programs that have touched nearly 2,000 trainees, faculty and staff; centralization and optimization of previously fragmented research services to create innovative opportunities for users; $10.2M distributed for pilot studies to accelerate innovation; and researcher participation in new partnerships with our communities and across the CTSA National Consortium. In the renewal period, CTSA funding leveraged with robust institutional support will enable MICHR to pursue 5 Overarching Objectives: 1) Optimize training and mentoring to create the next generation of research teams and clinical and translational investigators; 2) Augment infrastructure and refine research services to reduce barriers and maximize research productivity across the entire translational research continuum; 3) Foster collaborations and leverage innovative approaches and technologies to catalyze discovery; 4) Enhance community- and practice-based partnerships to assure bi-directional learning, research, and implementation of findings to benefit health; 5) Actively lead and contribute to national CTSA Consortium activities and engage in cross-CTSA collaborations. These will be achieved by: expanding education into new areas to strengthen the pipeline of CTR investigators and deploying more flexible training tools; strengthening existing services and launching new ones to impact study start-up times and recruitment; employing major informatics investments to fully integrate the needs of CTR investigators into IT landscape; utilizing new practice-based research networks; expanding evaluation to efficiently assess and optimize our performance. MICHR will be the engine of improvement and innovation in the conduct of high-quality, high impact-clinical and translational research to advance the health of Michigan and the nation.