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中文摘要
翻译
仍然缺乏进行基础、临床和转化性研究的研究人员 优先病原体及防治这些病原体感染的方法。职业生涯 新英格兰地区卓越中心生物防御计划的发展 生物防御和新出现的疾病旨在增加所有高技能研究人员的队伍 关于优先病原体的研究方面。这项职业发展计划将把教育和 从基础科学和临床两个方面对优先病原体进行培训。的目标 该计划旨在招募处于职业生涯早期阶段的研究人员从事优先病原体的研究工作 通过基础科学和临床/翻译研究方面的培训,并为 在整个新英格兰地区为所有研究人员提供优先病原体研究的继续教育。 我们提出了个人项目和团体项目相结合的方案。其核心组件是 我们建议的个人计划是一项早期职业发展计划,用于招聘研究人员 优先病原体。这一职业发展计划的重点是及早识别和支持个人 对他们进行培训,并招募他们从事与优先病原体研究有关的职业。这方面的培训 该计划涵盖了广泛的基础实验室研究、人类受试者临床调查、 和翻译研究。奖项将资助申请者开展与以下方面相关的研究培训计划 优先病原体的持续时间为2年或3年,这将使他们为更独立的研究或 成功申请美国国立卫生研究院颁发的额外职业发展研究奖。 为了补充个人计划,我们提出了旨在促进 新英格兰生物医学科学界在病原体优先领域的继续教育 研究。我们建议的小组计划分为三个方面:(1)年度科学静修;(2)研讨会 系列;和(3)与新英格兰调查人员有关的专题讲习班 优先病原体。
英文摘要
There continues to be a paucity of researchers conducting basic, clinical, and translational research on priority pathogens and the methods to prevent and treat infections by these agents. The Career Development in Biodefense program of the of the New England Regional Center for Excellence for Biodefense and Emerging Diseases is designed to increase the pool of highly skilled investigators in all aspects of research on priority pathogens. This Career Development program will integrate educational and training efforts in priority pathogens from both the basic science and the clinical aspects. The objectives of this program are to recruit investigators at early stages in their careers into work on priority pathogens through training in basic science and clinical/translational research and to provide opportunities for continuing education for all investigators in priority pathogen research throughout the New England region. We propose a combination of individual programs and group programs. The central component of the individual programs we propose is an Early Career Development Program for Recruitment into Research on Priority Pathogens. The focus of this career development program is to identify and support individuals early on in their training and recruit them into careers relevant to research on priority pathogens. Training in this program spans the broad range of basic laboratory-based research, clinical investigation in human subjects, and translational research. Awards will fund applicants to conduct a research training program relevant to priority pathogens of 2 or 3 years in duration, which will prepare them for more independent research or to be successful applicants for additional career development research awards from the NIH. To complement the individual programs, we propose group educational opportunities designed to promote continuing education of the New England biomedical scientific community in areas of priority pathogen research. The group programs we propose fall into three areas: (1) an annual scientific retreat; (2) a seminar series; and (3) workshops on topics of relevance to New England investigators conducting research on priority pathogens.
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Human NLRP11 function in non-canonical inflammasome activation by bacterial pathogen LPS
  • 批准号:
    10563477
  • 项目类别:
  • 资助金额:
    $53.09万
  • 财政年份:
    2023
  • 负责人:
    Marcia B Goldberg
  • 依托单位:
Infectious Disease and Basic Microbiological Mechanisms
  • 批准号:
    9411265
  • 项目类别:
  • 资助金额:
    $0.63万
  • 财政年份:
    2016
  • 负责人:
    Marcia B Goldberg
  • 依托单位:
Bacterial cell envelope in polar positioning of autotransporter proteins
  • 批准号:
    8917850
  • 项目类别:
  • 资助金额:
    $26.1万
  • 财政年份:
    2014
  • 负责人:
    Marcia B Goldberg
  • 依托单位:
Bacterial cell envelope in polar positioning of autotransporter proteins
  • 批准号:
    8638264
  • 项目类别:
  • 资助金额:
    $21.75万
  • 财政年份:
    2014
  • 负责人:
    Marcia B Goldberg
  • 依托单位:
海外基金