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Gene-Environment Interactinos Training Program

Gene-Environment Interactinos Training Program
基因-环境相互作用培训计划
批准号:
8296318
负责人:
Alvaro Puga
金额:
$31.8万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-07-01 至 2015-06-30

项目摘要

项目成果

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中文摘要
翻译
基因与环境相互作用培训计划(GEITP)的目标是培养博士前和 博士后学生将精通环境暴露和遗传多样性 相互作用以改变疾病的发作。实现这一目标需要跨学科的团队方法 整合对遗传多样性、表观遗传改变、高通量基因组学的理解, 生物统计学、生物标志物和暴露评估方法。研究的合作努力 为了实现这一目标,需要教员、临床医生、博士后和博士前受训人员。一 导师团队的方法,结合了在接触领域备受尊敬的科学家的专业知识, 评估、遗传变异性、疾病生物标志物和个体化/定制药物将用于 在基因-环境相互作用的多个领域教育受训者。博士前培训将包括 除了学生的入学博士学位之外,还需要完成课程作业。计划,实验室轮换与 导师团队,并在暴露评估,高通量遗传学, 变异性测量和生物标志物或暴露和/或疾病。博士后培训将包括 实验室和人事管理计划,试点赠款申请,以及为期一年的密集赠款 写作研讨会,为他们的独立研究做准备。所有学员都必须参加 “基因组学、暴露和生物标志物技术”研讨会,将作为该研讨会的一部分创建。 计划,并在年度GEITP学生研讨会上展示研究成果。该计划将包括一个 专门的管理结构,以确保招聘到适当的学员,实现教育目标, 并且实现了该补助金的目标。
英文摘要
The goal of the Gene-Environment Interactions Training Program (GEITP) is to train pre-doctoral and postdoctoral students who will be versed in ways that both environment exposures and genetic diversity nteract to alter the onset of disease. Achieving this objective requires an interdisciplinary team approach integrating an understanding of genetic diversity, epigenetic alterations, high-throughput genomics, biostatistics, biomarkers, and exposure assessment approaches. The collaborative efforts of research faculty, clinicians, postdoctoral and pre-doctoral trainees are needed in order to meet this objective. A mentorship team approach, combining the expertise of well-regarded scientists in the areas of exposure assessment, genetic variability, biomarkers of disease, and individualized/tailored medicine will be used to educate trainees in multiple areas of gene-environment interactions. Predoctoral training will include required coursework in addition to the student's matriculated Ph.D. program, laboratory rotations with the team of mentors, and hands-on work in several areas of exposure assessment, high-throughput genetic variability measures, and biomarkers or exposure and/or disease. Postdoctoral training will include programs in laboratory and personnel management, pilot grant applications, and an intensive year long grant writing workshop to prepare them for independent research. All trainees will be required to attend "Technologies in genomics, exposure, and biomarkers" workshop, which will be created as part of this program, and present research results at an annual GEITP Student Symposium. This program will include a dedicated governance structure to assure that appropriate trainees are recruited, education goals are met, and the aims of this grant are achieved.
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Gene-Environment Interactions in the Fetal Origin of Adult Cardiac Disease
  • 批准号:
    8966688
  • 项目类别:
  • 资助金额:
    $47.91万
  • 财政年份:
    2014
  • 负责人:
    Alvaro Puga
  • 依托单位:
Transgenerational Inheritance of Epigenetic Effects of Polychlorinated Biphenyls
  • 批准号:
    8599612
  • 项目类别:
  • 资助金额:
    $32.7万
  • 财政年份:
    2013
  • 负责人:
    Alvaro Puga
  • 依托单位:
Gene-Environment Interactinos Training Program
  • 批准号:
    8889398
  • 项目类别:
  • 资助金额:
    $25.64万
  • 财政年份:
    2008
  • 负责人:
    Alvaro Puga
  • 依托单位:
Core--DNA Microarray Facility
  • 批准号:
    6618910
  • 项目类别:
  • 资助金额:
    $19.7万
  • 财政年份:
    2002
  • 负责人:
    Alvaro Puga
  • 依托单位:
海外基金