Pre-doctoral Research Training in Human Genetic Epidemiology

这个重新修订的博士前培训补助金申请，提交响应NIH PA-02-109，要求 支持在“跨文化”跨学科环境中培训未来的遗传流行病学家， 整合生物统计学和计算科学（遗传流行病学，生物统计学，统计遗传学， 和生物信息学）与生物科学（人类遗传学，分子生物学和基因组学），使用 非常成功和有效的实践方法。我们相对较新的博士前课程在“定量” 人类和统计遗传学”融合了传统和非传统的方法。的主要目标 该计划是：（1）培养遗传流行病学家和统计遗传学家的分子方法， 分子数据分析技术，（2）培养人类遗传学家的统计遗传学方法 和方法，以便他们能够胜任地分析他们生成的数据。我们相信这位博士预科生 该计划将有效地减少文化冲击，往往抑制遗传流行病学家， 充分参与跨学科研究。这项培训补助金的供资将支持这一新的 开发计划，将针对研究生的本科专业是在统计 科学或生物科学，并在另一个方面有一定程度的熟练程度。我们要求提供4 在第一年和第二年的6个插槽。我们的建议通过融合和整合来应对挑战 精心挑选的教学培训，更强调直接动手学习的形式， 在华盛顿大学取得了巨大的成功。这项培训计划的一大优势是， 整个DBBS庞大的资源和丰富的跨学科培训环境，以及 另一个硕士学位培训计划（GEMS），也提供给所有博士前的学生在 这个戒酒会这我们希望，通过让我们的学生充分了解成熟的DBBS的广度和深度， 计划和资源，我们正在确保我们的学生将完全融入生物医学 以非常自然的方式学习科学，从而确保有效的“跨文化”培训。我们相信我们的 培训计划非常符合PA的精神，渴望培养未来的遗传流行病学家， 在当前的市场上，对合作生物医学研究的需求很大。

This re-revised pre-doctoral training grant application, submitted in response to NIH PA-02-109, requests support to train future Genetic Epidemiologists in a "cross-culture" interdisciplinary environment by integrating biostatistical and computational sciences (genetic epidemiology, biostatistics, statistical genetics, and bioinformatics) with biological sciences (human genetics, molecular biology, and genomics) using a highly successful and effective hands-on approach. Our relatively new pre-doctoral program in "Quantitative Human and Statistical Genetics" blends traditional and non-traditional approaches. The primary objectives of this program are: (1) To train Genetic Epidemiologists and Statistical Geneticists in molecular methods and molecular data analysis techniques, and (2) To train Human Geneticists in statistical genetics approaches and methods so that they can analyze competently the data they generate. We believe that this pre-doctoral program will effectively minimize the culture shock that often inhibits genetic epidemiologists from participating fully in interdisciplinary research. Funding of this training grant will support this newly developed program which will target graduate students whose undergraduate major was in either statistical sciences or biological sciences with some degree of proficiency in the other. We are requesting funds for 4 slots in the first year and 6 thereafter. Our proposal rises to the challenge by blending and integrating carefully chosen didactic training with greater emphasis on a direct hands-on learning format found to be immensely successful at Washington University. One of the great strengths of this training program is that the vast established resources and rich interdisciplinary training environment of the entire DBBS, as well as that of another masters degree training program (GEMS), are also available to all pre-doctoral students in this program. It is our hope that, by exposing our students to the full breadth and depth of the mature DBBS programs and resources, we are ensuring that our students will be fully integrated with the biomedical sciences in a very natural manner thus also ensuring effective "cross-culture" training. We believe that our training program is very much in the spirit of the PA, aspiring to produce future genetic epidemiologists in much demand in the current market place for pursuing collaborative biomedical research.