National Research Service Award Institutional Research Training Grants (T32)

描述(由申请人提供)： 这是我们第一次为爱荷华大学儿童医院的儿童血液学和肿瘤学机构培训赠款竞争续期，该培训赠款由NHLBI和NICHD联合赞助。我们最初建议将重点放在翻译和临床研究方面的培训上，目的是招募更多的女性和少数族裔从事学术工作。我们非常成功，因为迄今招募的五名研究员中有三名是妇女，两名是少数族裔候选人。此外，这两名已经毕业的女研究员，其中一人也是少数族裔实习生，都在儿科的初级教员职位上，积极从事临床研究。我们现在要求继续培训医生/科学家，他们将为改善血液疾病和恶性肿瘤儿童的诊断、治疗和预防策略做出贡献。我们寻求为博士生增加一个职位，因为我们已经意识到基础科学家对于成功的翻译和临床研究是多么重要。我们计划在我们的项目中继续专注于招募和培训女性，因为像许多儿科专科培训项目一样，我们爱荷华州的儿科系招募的住院医生中，女性比男性多，但在接受专科培训和从事学术医学职业的研究员队伍中，大多数女性都会流失。扭转学术界人才流失的局面，对于培养下一代医生和科学家至关重要，他们将专注于改善对患有血液和肿瘤疾病的儿童的护理。因此，我们提出以下具体目标以实现我们的目标：1.扩大受训人员追求学术生涯的机会，重点是血液病和儿童恶性疾病。2.为学员提供获得转化医学或临床医学硕士或非学位证书的机会。3.招募和培训妇女和少数族裔候选人，争取成功的职业，使患有血液病和肿瘤病的儿童受益。

DESCRIPTION (provided by applicant): This is our first competing renewal for this institutional training grant in Hematologic and Oncologic Diseases of Childhood at the University of Iowa Children's Hospital which is jointly sponsored by NHLBI and NICHD. We initially proposed to focus on training in translational and clinical research with the intent of recruiting more women and minorities for academic careers. We were highly successful as three of five fellows recruited to date have been women and two have been minority candidates. Moreover, the two female fellows who have "graduated", one of whom is also a minority trainee, are both in junior faculty positions in Departments of Pediatrics where they are actively engaged in clinical research. We are now asking to continue training physician/scientists who will contribute to improved diagostic, treatment and prevention strategies for children with blood diseases and malignancies. We seek to add one position for a PhD fellow because we have come to realize how important basic scientists are to successful translational and clinical research. We plan to continue to focus on recruiting and training women in our program because, like many pediatric subspecialty training programs, our Department of Pediatrics at Iowa recruits more women than men into residency, but loses most women from the ranks of fellows who obtain subspecialty training and pursue a career in academic medicine. Reversing this loss of talent in academia is crucial to training the next generation of physicians and scientists who will focus on improving care for children with hematologic and oncologic diseases. We therefore propose the following specific aims to accomplish our goals: 1. Expand opportunities for trainees to pursue academic careers with a focus on hematologic and malignant diseases of childhood. 2. Provide trainees with the opportunity to obtain a Master's degree or non-degree certification in either translational or clinical medicine. 3. Recruit and train women and minority candidates for successful careers that will benefit children with hematologic and oncologic disorders.