The Chemistry-Biology Interface Program at Johns Hopkins University

描述(由申请者提供)：本提案寻求对约翰·霍普金斯大学化学-生物学接口(CBI)培训计划的支持。目标是培养博士后学生使用化学和生物学工具进行生物医学研究。该计划是生物化学和分子生物学(彭博公共卫生学院)和药理学和分子科学系(医学院)的教职员工与他们在生物和化学系(Zanvyl Krieger艺术与科学学院)的同事共同努力的成果。学生参与者将在26个研究小组中有一系列不同的研究项目可供选择，包括合成、机理、酶学、分子成像和生物大分子结构。这些学生将接受生物和化学科学的课程培训，包括专门为该项目设计的为期两学期的化学生物学课程，但向所有约翰·霍普金斯大学的学生开放。CBI计划的其他方面包括CBI论坛，在那里学生将展示文学研讨会，为原创研究建议辩护，并为他们的论文辩护，以及年度务虚会。CBI项目于2005年秋季启动，由该大学提供资金，2006年秋季将有6名学生参加。随着该计划势头的增强，要求支持4名研究生，在3年级增加到6名学生。以咨询和指导的形式建立了广泛的支持网络，以最大限度地提高学生的成功。相关性：化学和生物学在基础和应用生物医学研究中的作用至关重要。对能够同时横跨两个科学领域的科学家的需求迅速增加。约翰霍普金斯大学的CBI项目将培养具有这种能力的科学家。

DESCRIPTION (provided by applicant): This proposal seeks support for a training program at the Chemistry-Biology Interface (CBI) at Johns Hopkins University. The goal is to train predoctoral students to carry out biomedical research using the tools of Chemistry and Biology. The Program is a collaborative effort between faculty in the Departments of Biochemistry and Molecular Biology (Bloomberg School of Public Health) and Pharmacology and Molecular Sciences (School of Medicine), with their colleagues in the Biology and Chemistry Departments (Zanvyl Krieger School of Arts & Sciences). Student participants will have a diverse array of research projects including synthesis, mechanism, enzymology, molecular imaging, and biomacromolecular structure to choose from in 26 research groups. The students will receive coursework training in the biological and chemical sciences, including a two-semester course in Chemical Biology designed especially for the Program, but open to all Johns Hopkins University students. Other aspects of the CBI Program include CBI Forum where students will present literature seminars, defend original research proposals, and defend their theses, as well as an Annual Retreat. The CBI Program was initiated in fall 2005 using funding from the University and will consist of 6 students in fall 2006. Support is requested to support 4 graduate students, increasing to 6 students in year 3, as the momentum of the Program increases. An extensive network of support in the form of advising and mentoring is in place to maximize the students' success. Relevance: The roles of chemistry and biology in basic and applied biomedical research are of paramount importance. There is a rapidly increasing need for scientists who can traverse both fields of science. The CBI Program at Johns Hopkins University will train scientists with this ability.