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中文摘要
翻译
药物遗传学、药效学和药代动力学分析实验室的使命 (3P)通过提供准确有效的最新数据来推进临床癌症研究, 药物遗传学、药效学和药代动力学参数分析。 3 P实验室为癌症中心成员提供三项服务,仪器,分析 服务和样品采集服务。 1.仪表 3 P实验室维护并指导癌症中心成员使用所有实验室设备 在3 P实验室工作。3 P实验室拥有1,200平方英尺的实验室空间和240平方英尺的 办公室面积超过25英尺,可容纳25台实验室仪器。这个空间是专门为 有效使用和维护分析仪器。实验室的设计也有利于及时和 有效处理临床样本。 2.分析服务 3 P实验室旨在开发和执行各种生物分析 方法,包括处理和分析PK/PD/PG研究的样本,以支持I、II、III期和 化学预防临床试验该服务包括开发和执行原始检测, 新试剂、监测内源性生化物质的测定、基因分型和突变测定以及 现有的分析方法(如适用)。 3.样品采集服务(SAS) 3 P实验室还为所有UWCCC临床试验提供样本采集服务。这一服务 提供给参与需要采集、处理、储存和运输的临床试验的所有研究者 用于PK/PD/PG研究的样本。
英文摘要
The mission of the Analytical Laboratory for Pharmacogenetics, Pharmacodynamics and Pharmacokinetics (3P) is to advance clinical cancer research by providing accurate and efficient state of the art data and analyses of pharmacogenetics, pharmacodynamics and pharmacokinetics parameters. The 3P Laboratory has three services available to Cancer Center members, instrumentation, analytical service and the sample acquisition service. 1. Instrumentation The 3P Laboratory maintains and instructs Cancer Center members on the use of all laboratory equipment housed in the 3P Laboratory. The 3P Laboratory has 1,200 square feet of laboratory space and 240 square feet of office space which house over 25 laboratory instruments. The space was specially designed for efficient use and maintenance of analytical instruments. The laboratory design also facilitates timely and efficient processing of clinical samples. 2. Analytical Services The 3P Laboratory is designed as a facility for developing and executing a wide variety of bioanalytical methods, including processing and analyzing samples for PK/PD/PG studies in support of Phase I, II, III and chemoprevention clinical trials. This service includes development and performance of original assays for new agents, assays to monitor endogenous biochemicals, genotyping and mutation assays and adaptation of existing methodology for analyses where applicable. 3. Sample Acquisition Services (SAS) The 3P Laboratory also offers a Sample Acquisition Service for all UWCCC clinical trials. This service is offered to all investigators participating in clinical trials requiring acquisition, processing, storage and shipping of samples for PK/PD/PG studies.
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Combating melanoma resistance by targeting ABL1/2
  • 批准号:
    10444295
  • 项目类别:
  • 资助金额:
    $63.48万
  • 财政年份:
    2022
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
Combating melanoma resistance by targeting ABL1/2
  • 批准号:
    10626076
  • 项目类别:
  • 资助金额:
    $57.15万
  • 财政年份:
    2022
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
Drug Discovery, Delivery, and Translational Therapeutics Research Program
  • 批准号:
    10470112
  • 项目类别:
  • 资助金额:
    $3.2万
  • 财政年份:
    2013
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
Drug Discovery, Delivery, and Translational Therapeutics Research Program
  • 批准号:
    10204892
  • 项目类别:
  • 资助金额:
    $3.2万
  • 财政年份:
    2013
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
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