INBRE: SOUTH CAROLINA STATE U: FACULTY AND UNDERGRADUATE RESEARCH DEVELOPMENT

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 南卡罗来纳州州立大学(SCSU)是南卡罗来纳州12所高级公立高等教育机构之一，也是该州唯一一所历史上唯一的黑人公立四年制大学。大约93%的学生是非裔美国人。这所大学是一所土地赠与、男女同校的综合性教学机构，向4,500,000名学生授予学士、硕士、教育专家和博士学位，其中包括2007-2008年毕业的124名STEM本科生。该大学秉承这样的理念，即强大的研究计划和其他创造性努力为强大的方案和行政基础设施提供了基础。在南加州大学，SC-INBRE将在新兴生物医学领域建立急需的研究能力，通过提供手段发展生物医学科学的两个目标教员，包括新聘用的Saku Greene博士。参加INBRE还将极大地增加少数族裔学生的人数，使他们更好地准备在生物医学和生物信息学研究领域攻读学位和从事职业。科学、数学和工程技术学院还通过路易斯·斯托克斯南卡罗来纳州少数民族参与联盟(LS-SCAMP)和HBCU-UP计划等项目提供了一支强大的本科生研究人员队伍--这些都是NSF支持的倡议。目前，南卡罗来纳州70%的少数民族STEM本科学位来自该州的LS-SCAMP。南卡罗来纳州立大学的LS-SCAMP招生人数最多。由于LS-SCAMP和HBCU-UPS的努力，平均每年有120名学生参加暑期研究。值得注意的是，参加LS SCAMP的学生中有80%继续在STEM领域继续研究生学习。虽然这些学生中的许多人通过实习获得了生物医学经验，但很少有人在南卡罗来纳州立大学获得这种经验。随着南卡罗来纳州立大学继续建设其研究能力，我们建议大幅增加在生物医学研究方面接受过良好培训的少数族裔本科生的数量。我们预测，这些学生中的很大一部分将留在该州攻读该州授予博士学位的研究生学位，并作为研究科学家建立成功的职业生涯。 目前，该系有380名生物和化学专业的学生。这保证了有大量的学生参加INBRE项目。在五年的项目期内，将为50名学生提供尖端生物医学技术方面的专业知识。为了进一步让学生熟悉生物医学研究，还将设立INBRE生物医学研讨会系列。在本学年，南卡罗来纳大学、弗吉尼亚联邦大学和其他INBRE研究型大学的INBRE导师和其他杰出的研究科学家将被邀请作为研讨会演讲者来到南加州州立大学。预计将通过与INBRE科学家的这些关系开展更多的合作，例如在新提出的生物技术轨道和新的研究倡议的课程中担任客座讲师。在夏季期间，INBRE夏季生物医学研讨会系列将设立，并将要求学生每周开会讨论最近发表的生物医学文章。要求提供资金，以增加出席州内和全国生物医学研究会议的学生数量。 生物和物理科学系的生物技术选项被提出。目前，在生物、化学和物理领域有16门与生物医学有关的课程。然而，对于对生物医学感兴趣的学生来说，没有明确的核心序列或生物技术轨道。拟议的生物技术方案将在现有课程的基础上增加4门新的生物医学课程。新课程包括：分子和生物医学技术、分子和生物医学科学研究、医学微生物学和免疫学、细胞和分子生物学II和生物技术伦理学课程。每学期，INBRE的目标是教师，来自合作机构的客座讲师将负责教授组成这一新的生物技术轨道的至少一门课程。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. SC State University (SCSU) is one of 12 senior public post-secondary educational institutions in South Carolina and the state's only Historically Black public four-year university. Approximately 93% of the student population is African American. The university is a land-grant, co-educational, comprehensive, teaching institution that confers the baccalaureate, master's, educational specialist, and doctoral degrees to the 4,500  5,000 student population, including 124 undergraduate STEM students graduating in 2007-2008. The University embraces the concept that strong programs of research and other creative endeavors provide the basis for strong programmatic and administrative infrastructures. At SCSU, SC-INBRE will build much needed research capacity in emerging Biomedical fields, by providing the means to develop two target faculty in the Biomedical Sciences, including a new hire, Dr. Saku Greene. Participation in INBRE will also substantially increase the pool of minority students better prepared to pursue degrees and careers in biomedical and bioinformatics research. The College of Science, Mathematics and Engineering Technology also provides a significant contingent of undergraduate researchers through programs like the Louis Stokes South Carolina Alliance for Minority Participation Program (LS-SCAMP) and the HBCU-UP's program--all NSF supported initiatives. Currently, the state LS-SCAMP produces 70% of South Carolina's minority STEM undergraduate degrees. South Carolina State University has the largest LS-SCAMP enrollment. On the average, 120 students participate in summer research annually because of the efforts of LS-SCAMP and HBCU-UPS. It is significant to note that 80% of students involved in LS SCAMP go on to continue graduate studies in a STEM area. While many of these students gain biomedical experience through their internships, very few gain that experience at South Carolina State University. We propose to significantly increase the number of minority undergraduates who are well trained in biomedical research at South Carolina State University as the institution continues to build its research capacity. We predict that a large percentage of these students will remain in the state to pursue graduate degrees from the state's PhD granting institutions and establish successful careers as research scientists. Currently, there are 380 biology and chemistry majors in the department. This guarantees a large pool of students to recruit for participation in the INBRE program. A total of 50 students will be provided with expertise in cutting-edge biomedical techniques over the 5 year project period. To further familiarize students with biomedical research, an INBRE Biomedical Seminar series will also be established. During the academic year, INBRE mentors and other distinguished research scientists from the University of South Carolina, Virginia Commonwealth University and other INBRE research universities will be invited to SCSU as seminar speakers. It is anticipated that additional collaborations will develop from these relationships with INBRE scientists such as guest lecturers in courses in the newly proposed Biotechnology Track and new research initiatives. During the summer, the INBRE Summer Biomedical Seminar series will be established and will require that students meet weekly to discuss recently published biomedical articles. Funding is requested to increase the number of students who present at biomedical research conferences within the state as well as nationally. A Biotechnology option in the Department of Biological and Physical Sciences is proposed. Currently, there are 16 bio-medically-related courses in the Biology, Chemistry and Physics areas. However, there is no defined core sequence or biotechnology track for students interested in pursuing biomedicine. The proposed Biotechnology option will add 4 new bio-medically-focused courses to the existing courses. New courses include: Molecular and Biomedical Techniques, Research in Molecular and Biomedical Science, Medical Microbiology and Immunology, Cellular and Molecular Biology II and an Ethics in Bio-technology course. Each semester, INBRE target faculty, guest lecturers from partner institutions will be responsible for teaching at least one of the courses that comprise this new Biotechnology Track.