Seamless Energy Balance Monitoring Solution for Personal Fitness and Clinical Res

描述(申请人提供)：Valencell开发了一种移动传感器技术，称为Healthset(R)技术，用于通过无线音频耳机监测生命体征和身体活动。这种高度小型化的传感器技术可以集成到音频耳机、耳机、助听器和耳饰中，以实现对能源消耗的无缝移动监控。Valencell的长期目标是增强Healthset技术，以提供无缝的移动能量平衡监测解决方案，集成到单一的、可穿戴的、无线的、高度小型化的音频耳机中。这一移动解决方案将满足几个迫在眉睫的公众需求：1)用于疾病预防和健康管理的一体式可穿戴能量平衡监测仪的临床需求；2)便携式、自动化生理数据收集工具的学术需求；以及3)消费者对引人入胜的移动健康评估平台的需求。这一二期计划的具体目标是在临床上验证一个可扩展的无缝能量消耗监测平台。这项工作将涉及实施对Healthset传感器技术的改进，以及优化将传感器指标与能源消耗相关联的统计模型。此外，将实施和验证将能源消耗监测(通过Healthset技术)与能源摄入量监测(通过第三方网络应用程序)相结合的移动解决方案。这一移动解决方案将用户的无线Healthset耳机和移动手机与第三方移动网络应用程序(如食物和体重日记)连接起来，合并后的数据将被处理，以提供有意义和有用的能量平衡指标。这一移动解决方案将允许第三方应用程序向Healthset平台提供重要的能量摄入数据，包括食品日记和无线秤，以及大学、政府实验室和行业目前正在开发的新兴传感器技术。在NIH第二阶段计划中，Valencell将：1)为移动能源支出监测制造并鉴定第二阶段Healthset原型；2)优化统计模型以估计总能源支出(TEE)和静息(REE)能源支出；3)实施将能源支出与能源摄入相结合的无缝移动解决方案；以及4)在现场环境中验证移动解决方案。这一二期工程将展示一个无缝的能量平衡监测平台，适合在三期工程中过渡到大规模商业化。 公共卫生相关性：可改变的健康风险因素，如高压力、不良饮食和久坐不动的生活方式，占全球所有医疗费用的25%，每年导致数百万人死亡。无缝移动能量平衡监测可以让个人过上更健康的生活，节省数万亿的医疗费用。这项第二阶段计划中提出的技术将有助于使健康的生活方式更容易、更有效、更负担得起。

DESCRIPTION (provided by applicant): Valencell has developed a mobile sensor technology - called Healthset(R) technology - for monitoring vital signs and physical activity via a wireless audio earbud. This highly miniaturized sensor technology can be integrated into audio headsets, headphones, hearing aids, and ear jewelry for seamless mobile monitoring of energy expenditure. Valencell's long-term goal is to augment Healthset technology to provide a seamless mobile energy balance monitoring solution, integrated within a single, wearable, wireless, highly miniaturized, audio earpiece. This mobile solution will satisfy several imminent public needs: 1) the clinical need for an all-in-one wearable energy balance monitor for disease prevention and health management, 2) the academic need for a portable, automated physiological data collection tool, and 3) the consumer demand for an engaging, mobile fitness assessment platform. The specific goal of this Phase II program is to clinically validate a scalable and seamless energy expenditure monitoring platform. This work will involve implementing improvements to Healthset sensor technology as well as optimizing the statistical models relating sensor metrics to energy expenditure. Furthermore, a mobile solution for integrating energy expenditure monitoring (via Healthset technology) with energy intake monitoring (via 3rd party web applications) will be implemented and validated. This mobile solution will connect the user's wireless Healthset earbud and mobile handset with 3rd party mobile web applications (such as food and weight diaries), and the combined data will be processed to provide a meaningful and useful energy balance metric. This mobile solution will allow 3rd party applications to provide important energy intake data to the Healthset platform, including food diaries and wireless scales, as well as emerging sensor technologies currently under development by universities, government labs, and industry. In this NIH Phase II program, Valencell will: 1) fabricate and qualify Phase II Healthset prototypes for mobile energy expenditure monitoring, 2) optimize statistical models for estimating total (TEE) and resting (REE) energy expenditure, 3) implement a seamless mobile solution integrating energy expenditure with energy intake, and 4) validate the mobile solution in a field environment. This Phase II program will demonstrate a seamless energy balance monitoring platform that is suitable for transitioning to large-scale commercialization in a Phase III program. PUBLIC HEALTH RELEVANCE: Modifiable health risk factors such as high stress, poor diet, and a sedentary lifestyle account for 25% of all medical expenses and millions of deaths per year worldwide. Seamless mobile energy balance monitoring can empower individuals to live healthier lives, saving trillions in medical expenses. The technology proposed in this Phase II program will help make healthy lifestyles easier, more effective, and more affordable.