Seamless energy balance monitoring device

描述（由申请人提供）：尽管市场对消费者友好型能量平衡监测仪的需求不断增长，但目前还没有满足消费者需求的商业解决方案。Valencell的长期目标是提供一个无缝的、可穿戴的健康和健身监测平台，该平台具有自主、用户友好、日常使用舒适、多种生活活动准确，并能够向用户提供可操作的反馈。这个预防性医疗保健平台将为最终用户、他们的医生和培训师提供易于使用、可操作的反馈，促进健康的生活方式。Valencell此前开发并测试了一款名为Healthset的自主可穿戴健康和健身监测器，它可以测量生命体征和身体活动，并将这些信息以图形形式呈现在智能手机上。虽然Healthset(R)测量各种强度水平的体力活动，但它不包含从原始体力活动数据处理能量消耗评估的算法。实验证据表明，Valencell的Healthset(R)算法可以增强，为日常生活活动提供准确的能量消耗评估，适用于临床、学术和消费者应用。因此，第一阶段可行性研究的具体目标是验证Healthset(R)作为一种无缝的能源消耗监测工具。在NIH的I期项目中，Valencell和杜克大学的合作者将：1.)制造预先设计的用于测量能量消耗的优化Healthset单元，2.)在10人间接量热研究中收集时间相关的Healthset(R)数据，3.)生成能量消耗的统计模型，4.)在第二次临床研究中验证这些模型。第一阶段项目将提供用于多种体育活动的Healthset(R)能量消耗监测器的初步性能规范。评估卡路里消耗的机会也将在最终报告中讨论，以建立一个完整的能量平衡监测平台。公共卫生相关性：高压力、不良饮食和久坐不动的生活方式等可改变的健康风险因素占全球医疗费用的25%，每年造成数百万人死亡。无缝、准确、实时的个人健康和健身反馈可以让个人过上更健康的生活，节省数万亿美元的医疗费用。第一阶段SBIR中提出的能量平衡监测技术将使健康生活更容易、更有效、更实惠。

DESCRIPTION (provided by applicant): Despite the growing market demand for a consumer-friendly energy balance monitor, there are no commercially available solutions satisfying consumer needs. Valencell's long-term goal is to provide a seamless, wearable platform for health and fitness monitoring that is autonomous, user-friendly, comfortable for daily use, accurate in multiple life activities, and able to provide actionable feedback to the user. This preventive healthcare platform will provide end users, their doctors, and their trainers with easy-to-use, actionable feedback promoting a healthy lifestyle. Valencell has previously developed and alpha-tested the Healthset(R), an autonomous wearable health and fitness monitor that measures vital signs and physical activity and presents this information graphically on a smartphone. While the Healthset(R) measures physical activity of various intensity levels, it does not contain algorithms for processing energy expenditure assessments from raw physical activity data. Experimental evidence suggests that Valencell's Healthset(R) algorithms can be augmented to provide accurate energy expenditure assessments for daily life activities, suitable for clinical, academic, and consumer applications. Thus, the specific goal of this Phase I feasibility study is to validate the Healthset(R) as a seamless energy expenditure monitoring tool. In this NIH Phase I program, Valencell and collaborators at the Duke University will: 1.) fabricate pre-designed Healthset units optimized for measuring energy expenditure, 2.) collect time-correlated Healthset(R) data in a 10-person indirect calorimetry study, 3.) generate statistical models for energy expenditure, and 4.) validate these models in a second clinical study. This Phase I program will deliver the preliminary performance specifications for the Healthset(R) energy expenditure monitor used in multiple physical activities. The opportunity for assessing calories consumed will also be addressed in the final report for a complete energy balance monitoring platform. PUBLIC HEALTH RELEVANCE: Modifiable health risk factors such as high stress, poor diet, and a sedentary lifestyle account for 25% of all medical expenses and millions of deaths per year worldwide. Seamless, accurate, real-time feedback on personal health and fitness can empower individuals to live healthier lives, saving trillions in medical expenses. The energy balance monitoring technology proposed in this Phase 1 SBIR would make healthy living easier, more effective, and more affordable.