Bridging Efficacy and Effectiveness in Drug Abuse Treatment

描述（由申请人提供）：本提案的总体目标是支持申请人作为药物滥用治疗干预发展领域的新独立研究精神病学家的持续发展。提交K02是为了继续申请人的K23开发，这使他能够获得该领域的独立研究支持。在过去的五年中，申请人一直在进行成瘾障碍领域的治疗发展，流行病学和服务研究。通过K02奖，申请人寻求在继续发展其职业生涯的同时深化这一工作。拟议的研究项目的统一主题是发展干预措施，以改善有或没有共同发生的障碍的成瘾的结果。该计划的重点将放在开发可在社区环境中使用的干预措施上，从而达到效果和效果之间的桥梁。这个K02是围绕三个项目建立的。第一个项目“SMART：改善药物滥用诊所精神疾病共病的检测和治疗”（DA020783）的目标是开发一种干预措施，以解决社区诊所治疗共病的主要障碍。由纽约州酒精和药物滥用服务办公室资助的第二个项目“青少年病态赌博治疗”的目标是为这一人群开发一种手动CBT。第三个项目“西语裔药物滥用”（DA019606）旨在为西语裔制定预防和治疗方案奠定经验基础。成瘾领域需要临床医生-研究人员，他们可以在疗效和有效性研究之间架起桥梁，该奖项将通过与这些领域的专家合作和培训，提高申请人在成功开展这项工作所必需的方法上的技能。申请人职业规划的其他组成部分包括行为干预策略、生物统计学和继续伦理培训方面的高级培训。最后，申请人将为各种教育活动做出贡献，并承担越来越重要的指导角色。在申请人所在机构的大力支持下，本申请中提出的活动的计划结果将是培养一名能够规划和开展研究的科学家，这些研究将在成瘾障碍的治疗中架起疗效和有效性的桥梁。

DESCRIPTION (provided by applicant): The overall aim of this proposal is to support the continuing development of the applicant as a newly independent research psychiatrist in the field of interventions development for drug abuse treatment. This K02 is submitted to continue the applicant's development initiated with a K23, which permitted him to obtain independent research support in this field. Over the last five years the applicant has been conducting studies of therapy development, epidemiology and services research in the area of addictive disorders. Through the K02 award, the applicant seeks to deepen this line of work while continuing the development of his career. The unifying theme of proposed program of research is the development of interventions to improve the outcome of addictions with and without co-occurring disorders. The emphasis of the program will be on development of interventions that can be used in community settings and, thus, bridge efficacy and effectiveness. This K02 is built around three projects. The goal of the first project, "SMART: Improving Detection and Treatment of Psychiatric Comorbidity in Substance Abuse Clinics" (DA020783), is to develop an intervention to address key barriers to the treatment of co-occurring disorders in community clinics. The goal of second project, "Treatment for Adolescents with Pathological Gambling" funded by the New York State Office of Alcohol and Substance Abuse Services, is the development of a manualized CBT for this population group. The third project "Substance Abuse in Hispanics" (DA019606) seeks to establish an empirical foundation to develop prevention and treatment programs for Hispanics. The field of addiction needs clinicians-researchers who can bridge efficacy and effectiveness research, and this award will permit enhancement of the applicant's skills in the methods necessary to successfully conduct this work, through collaboration and training with experts in these fields. Other components of the applicant's career plan include advanced training in behavioral intervention strategies, biostatistics and the continuation of ethics training. Finally, the applicant will contribute to various educational activities and assume a progressively more important mentoring role. The planned outcome of the activities proposed in this application, with the strong support of the applicant's institution, will be the development of a scientist capable of planning and conducting research that will bridge efficacy and effectiveness in the treatment of addictive disorders.