C1 - Administrative Core

计划为此核心所做的工作是以 上一期的PPG实现了高生产率和高效率的整合。这个核心是PPG的枢纽 在不对个别项目团队进行微观管理的情况下，提供行政支持和指导。 核心将负责定期安排、组织、主持和/或促进 支持PPG进展的会议。这些会议包括(一)-全体会议(包括 顾问)、(二)--电子会议、(三)--由私营部门小组参加的研究小组专题会议 参加国内和国际会议的团队。核心负责旅行的管理 支持这些会议，包括资金的分配和核算。核心令人信服 遵守所有机构、政府和国家卫生研究院特定的法规和要求，包括 及时与NIH沟通，并向NIH报告进展情况。所有财务报告和协调 包括国内外几个主要机构的PPG的各个方面也得到了管理 通过核心活动。其他管理目标是确保关于 分配(和重新分配)资源、项目预期和进度，以及实现以下目标 PPG得到了适当、公平、深思熟虑和及时的处理。因此，核心将 继续发挥作用，确保PPG的科学发现和传播产生尽可能大的影响 国家活动(L)--提供必要的监督、协调和行政支持 确保PPG及其联合体活动的最佳表现；(2)-在 PPG的计算生物学和生物信息学方面，包括资源共享和共享 以及(3)--开发信息管理系统 PPG所代表的研究领域的系统，包括计算机辅助专家 标注系统传输器标注中心(TRAC)和相关文献挖掘工具 车钩。 相关性(请参阅说明)： 我们研究了一组复杂的细胞机器和功能，通过协调的科学努力来理解 对维持人类健康和防治疾病至关重要的机制，如药物滥用。带来 我们以高效和协调的方式共同努力，使用一个行政核心，以促进 最高标准的科学研究，遵守所有规章制度，并分享 拉雷财团和社区内的资源和结果

The efforts planned for this Core, are modeled on the components that have been demonstrated in the previous period of the PPG to enable high productivity and efficient integration. This core is a hub of PPG activities and provides administrative support, and guidance without micromanaging individual project teams. The Core will be responsible for scheduling, organizing, hosting and/or facilitating on a regular basis the meetings that support the progress ofthe PPG. These meetings include (i)-plenary meetings (including Advisors), (ii)-electronic meetings, (iii)-thematic meetings of research groups enabled by participation of PPG teams in National and International conferences. The Core is responsible forthe administration of travel support for these meetings, including the allocation and accounting of funds. The Core is assuring compliance with all institutional, governmental and NIH-specific regulations and requirements, including timely communication with, and Progress Reporting to the NIH. All financial reporting and coordination aspects ofthe PPG that encompasses several major Institutions here and abroad are managed as well through the Core activities. Additional management objectives are to make certain that decisions about allocation (and reallocation) of resources, project expectations and progress, and accomplishing the goals of the PPG are addressed appropriately, fairly and in a well thought out and timely manner. The Core will thus continue to function to ensure the highest possible impact ofthe PPG's scientific discovery and dissemi¿¿ nation activities by (l)-providing the necessary oversight, coordination and administrative support that will ensure the optimal performance of the PPG and its Consortium activities; (2)-providing services in the computational biology and bioinformatics aspects ofthe PPG, including resource sharing, and the sharing and dissemination of data generated by this Consortium; and (3)-developing an Information Management System forthe area of research represented by the PPG, including the computer-facilitated expert annotation system TRansporter Annotation Center (TRAC), and the associated literature-mining tool Coupler. RELEVANCE (See instructions): We study a complex set on cellular machines and functions in a coordinated scientific effort to understand mechanisms essential to maintaining human health and combating disease, such as drug abuse. To bring these efforts together in an efficient and coordinated manner we use an administrative core that fosters the highest standards of scientific research, compliance with all rules and regulation, and the sharing of resources and rasults within the Consortium and the communitv at larae