Medical Scientist Training Program

描述(由申请者提供)：阿拉巴马大学伯明翰分校(UAB)医学科学家培训计划(MSTP)的重点是培养优秀的年轻人成为一名科学研究人员和一名训练有素的医生。尽管个别受训者的最终职业道路可能从进行基础生物医学研究到进行新型治疗剂或程序的临床试验，但这批研究人员的净效果将是将基本生物医学知识更多地转化为临床实践。我们的计划旨在(1)在基础科学教育和临床教育的基础上提供一流的课堂培训；(2)培训学生成为成功的生物医学科学家所必需的工具，包括资助和手稿写作以及时间和实验室管理；以及(3)毕业内科医生-科学家，他们后来成为全国学术医学中心的领导者。UAB的MSTP课程的基本结构类似于大多数课程，分为三个不同的阶段--两年的基础科学课程工作和夏季实验室轮换(临床前阶段)，延长的实验室研究阶段，以获得博士学位(研究阶段)，然后是临床培训，以获得医学博士学位(临床阶段)。我们计划的一个关键区别是，学生在头两年既要学习研究生院的课程，也要学习医学院的课程，并将门诊办事员的工作整合到他们的研究生年中。我们的MSTP学生可以选择在校园内的多个学位授予项目中攻读博士学位，并将在我们基于主题的新项目中获得研究生课程，这些项目包括癌症生物学、人类病理学、免疫学、微生物学、神经科学、遗传学、生物医学工程和生物化学。完成我们项目的平均时间为7.9年。该项目通常每年招收8名学生，目前在校学生总数为58人。在本年度，UAB MSTP T32奖为12个名额提供了支持，尽管研究科批准了14个名额。在这项申请中，我们建议在五年内将培训名额增加到总共20个。 公共卫生相关性：过去30年生物医学科学的快速发展导致了对训练有素的研究人员的迫切需求，这些研究人员也直接参与临床医学，将生物医学科学的多项新发现转化为可行的临床应用。联合培训现代医学中最杰出的个人以及基础生物医学科学的特殊智力观点和技术诀窍是满足这一需求的关键组成部分。

DESCRIPTION (provided by applicant): The focus of the Medical Scientist Training Program (MSTP) at the University of Alabama at Birmingham (UAB) is to train outstanding young people in the intellectual discipline of being a scientific investigator and a thoroughly trained physician. Although the ultimate career pathway for individual trainees may range from the conduct of basic biomedical research to clinical trials of novel therapeutic agents or procedures, the net effect of this cadre of investigators will be to increase the translation of basic biomedical understanding into clinical practice. Our Program aims to (1) offer superb classroom training in both basic science education and the fundamentals of clinical education; (2) train students in the tools necessary to become successful biomedical scientists, including grant and manuscript writing and time and laboratory management; and (3) graduate physician-scientists who go on to become leaders in academic medical centers throughout the country. The basic structure of the MSTP curriculum at UAB is similar to most programs with three distinct phases - two years of basic science course work and laboratory rotations in the summers (Pre-clinical Phase), an extended period of laboratory research leading to the PhD (Research Phase), followed by a clinical training leading to the MD degree (Clinical Phase). One key difference in our program is that students take both graduate school coursework and medical school coursework during their first two years and integrate an ambulatory clinic clerkship into their graduate years. Our MSTP students can choose to do their PhD in multiple degree-granting programs on campus and will get their graduate coursework in our new theme based programs, which include cancer biology, human pathoblology, immunology, microbiology, neuroscience, genetics, biomedical engineering, and biochemistry. The average time to complete our program is 7.9 years. The program usually accepts 8 students each year and currently has a total student body of 58 active students. In the current year, the UAB MSTP T32 award provided support for 12 slots, although the study section approved 14 slots. In this application, we propose an increase to a total of 20 training slots over a five-year period. PUBLIC HEALTH RELEVANCE: The rapid advances in biomedical sciences of the past 30 years has resulted in a critical need for well trained investigators who also have direct involvement with clinical Medicine to translate the multiple new discoveries in biomedical science into workable clinical applications. Joint training of the most outstanding individuals in both modern medicine and the special intellectual perspective and technical know-how of basic biomedical science is a key component of meeting this need.