Administrative Core

印第安纳州儿科药理学中心（ICPP）是一个高度合作的多学科研究人员小组，他们已经合作了近十年。其研究重点是生殖细胞基因组学对儿童药物疗效和安全性的影响。该中心代表了跨学科合作的高效模式，对这一研究领域产生了重大影响，并产生了大量支持这一应用的初步数据。的 行政核心涉及五位关键领导人：弗洛克哈特博士。伦巴格哈妮琳罗伯逊和比斯。该领导小组对由ICPP PI Renbarger博士和Flockhart博士管理的核心进行密切的战略监督。核心的目标是：1）组织ICPP项目和核心内部和之间的沟通，包括：作为财务管理的沟通结构，维护所有中央文件，组织协作手稿和提案准备，以及维护定期会议和电话会议时间表;以及2）组织三个项目，生物统计学和建模核心以及基因分型和分析实验室之间的有效数据流。 该核心是管理所产生的大量数据的核心，并负责这些数据的审计和质量控制：它是IPCC研究中心的协调引擎。从项目中生成的所有临床、基因组、蛋白质组和体外数据都被发送到核心，在那里它们被存储在caArray安全数据管理系统中，然后被发送到生物统计和建模核心进行分析，因为数据是从特定项目和试点中生成的。行政核心服务于所有项目，是项目与生物统计和建模核心之间沟通的主要组织者。核心小组还负责协调和组织这些调查员之间广泛的定期互动。这些包括国家和国际科学会议，每周电话/网络会议，每月执行委员会会议和每年与我们的科学咨询委员会务虚会。

The Indiana Center for Pediatric Pharmacology (ICPP) is a highly collaborative group of multidisciplinary investigators that have worked together productively for almost a decade. Its research has focused on the effects of germ line genomics on the efficacy and safety of medications for children. The center represents a highly productive model of interdisciplinary collaboration, that has significantly impacted this field of investigation, and generated a large amount of preliminary data that support this application. The Administrative Core involves five key leaders: Drs Flockhart. Renbarger. Haneline. Robertson and Bies. This leadership group provides close, strategic oversight of the Core, which is managed by Drs. Renbarger and Flockhart, the ICPP PIs. The Aims of the core are: 1) To organize communication within and between the ICPP projects and cores, including: serving as a communication structure for fiscal management, maintaining all central documents, organizing collaborative manuscript and proposal preparation, and maintaining of regular meeting and teleconference schedule; and 2) To organize the effective flow of curated data between the three projects, the Biostatistics and Modeling Core, and the genotyping and analytical labs. This Core is central to the management of the large amounts of data generated, and is responsible for the auditing and quality control of that data: it is the coordinating engine at the center of the IPCC's research. All clinical, genomic, proteomic, and in vitro data generated from projects are sent to the core, where they are stored in the caArray secure data management system before being sent to the Biostatistics and Modeling Core for analysis as data are generated from specific projects and pilots. The Administrative Core serves all projects and is the key organizer of communication between the projects and the Biostatistics and Modeling core. The Core is also responsible for the coordination and organization of the wide range of regular interactions of these investigators. These include national and international scientific meetings, weekly phone/web conferences, monthly executive committee meetings and yearly retreats with our scientific advisory committee.