2012 International Conference on Gram-positive Pathogens

描述（由申请人提供）：由革兰氏阳性病原体引起的感染，包括金黄色葡萄球菌、化脓性链球菌、艰难梭菌和屎肠球菌等，是我们社会的负担，导致显著的发病率和死亡率。2012年国际革兰氏阳性病原体会议（ICGPP）旨在通过促进研究革兰氏阳性发病机制和生物学多个方面的研究人员之间的互动，更好地了解这些细菌。我们正在申请资金，以部分支持2012年ICGPP，该会议将于2012年10月7日至10日在美国东北部的奥马哈举行。我们已经确保了五位国际公认的主讲人的参与，他们将专注于细菌代谢在调节发病机制和宿主与病原体之间的界面中的功能。ICGPP的一个重要优先事项是博士生前和博士后学员的积极参与；对于那些喜欢做口头报告的年轻科学家，我们将给予充分的照顾。本次会议的最终目标是通过新的合作来扩大我们对革兰氏阳性发病机制和生物学的理解，并通过研究这些相关病原体的类似系统获得新的见解。

Description (as provided by the applicant): Infections caused by gram-positive pathogens, including Staphylococcus aureus, Streptococcus pyogenes, Clostridium difficile, and Enterococcus faecium, among others, are a burden on our society causing significant morbidity and mortality. The 2012 International Conference on Gram-Positive Pathogens (ICGPP) seeks to better understand these bacteria through fostering interactions between investigators studying multiple aspects of gram-positive pathogenesis and biology. We are applying for funds to support, in part, the 2012 ICGPP, which will be held in Omaha, NE on October 7-10, 2012. We have secured the participation of five internationally recognized keynote speakers that will focus on the function of bacterial metabolism in the regulation of pathogenesis and the interface between host and pathogen. A significant priority of the ICGPP is the active participation of pre- and post-doctoral trainees; every accommodation will be given to those junior scientists who prefer to give oral presentations. Ultimately, the goal of this conference is to broaden our understanding of Gram- positive pathogenesis and biology through the generation of new collaborations and to gain new insights through the study of similar systems in these related pathogens. Public Health Relevance: The International Conference on Gram-Positive Pathogens (ICGPP) provides a forum where investigators studying multiple aspects of gram-positive pathogenesis and biology can interact and share ideas to enhance the general understanding of these important pathogens. These interactions will foster new ideas and collaborations to ultimately develop novel therapeutic regimens to treat these sometimes devastating infections.