Data Management and Biostatistics Core

数据管理和生物统计学核心（DBMC）的使命是确保我们的国际中心， 卓越疟疾研究（ICEMR）有效和高效地设计，进行，分析和报告 重要的现场和实验室研究，数据可以在内部的站点之间集成和组合 研究和跨研究。核心将建立可重复研究的基础设施，并将 与现场调查员合作，逐步提高现场在整个 赠款期限。核心小组将参与面对面和网络教育活动。这些特派团 将由具有统计、数据库和信息技术（IT）专业知识的工作人员提供支持， IT基础设施，满足我们的目标，同时根据现场实际情况进行调整。高质量的信息 技术，包括网上资料输入、电脑保安、资料管理及表格设计、研究 设计，进行分析和报告，对于确保我们的ICEMR研究是最高的 质量. DMBC成员将与霍普金斯和实地工作人员合作进行研究设计，进行分析 和报告。活动将包括制定研究问题;将这些问题转化为统计数据; 支持样本量确定和其他设计方面的设计和分析。DMBC将 组织其工作人员和其他研究者每周开会，讨论与研究设计相关的问题 分析，并评估发展新的统计方法的需要。日程安排将允许现场 工作人员通过电话会议参与，共同讨论将鼓励广泛投入。这些 会议将提供一个多学科讨论的论坛，讨论设计、指挥和分析问题以及信息技术 问题.重要的，可操作的研究项目将出现，这将改善研究的进行，并具有更广泛的 影响教育目标和责任将是双向的，在巴尔的摩和外地的教育目标和责任将是双向的， 网站将提供很多东西，并相互学习。我们的共同责任文化，DMBC 工作组会议和产生的研究项目，以及其他合作场所将有助于 实现共同的教育目标。这些目标包括加强对以下方面的了解和参与/领导 在统计设计、进行和分析、表格编制、网络实施和其他信息技术问题方面。 DMBC通过数据管理和生物统计学适应实地现实， 这是我们研究有效性的重要组成部分。

The Data Management and Biostatistics Core (DBMC) mission is to ensure that our International Center of Excellence in Malaria Research (ICEMR) effectively and efficiently designs, conducts, analyzes and reports important field and laboratory studies with data that can be integrated and combined among sites within studies and across studies. The Core will establish the infrastructure for reproducible research and will collaborate with investigators at the field sites to progressively enhance the sites' capabilities throughout the term ofthe grant. The Core will engage in in-person and web-based educational activities. These missions will be enabled by staff with statistical, database, and information technology (IT) expertise, empowered by an IT infrastructure that meets our goals while being tuned to field realities. High quality information technology including web-based data entry, computer security, data management and forms design, study design, conduct analysis and reporting, are essential for assuring our ICEMR studies are ofthe highest quality. DMBC members will collaborate with Hopkins and field staff on research design, conduct analysis and reporting. Activities will include formulation of research questions; translation of these into statistical designs and analyses that support sample size determination and other design aspects. The DMBC will organize weekly meetings among its staff and other investigators to discuss issues related to study design and analysis, and to assess needs for the development of new statistical methods. Scheduling will allow field staff to participate via teleconference, and shared agenda-setting will encourage broad input. These meetings will provide a forum for multi-disciplinary discussion of design, conduct, and analysis issues and IT issues. Important, actionable research projects will emerge that will improve study conduct and have broader impact Educational goals and responsibilities will be bi-directional in that those in Baltimore and in the field sites will have much to offer and to learn from each other. Our culture of shared responsibility, the DMBC working group meetings and the generated research projects, and other collaborative venues will help achieve joint educational goals. These goals include increased understanding of and participation/leadership in statistical design, conduct and analysis, forms development, web implementation and other IT issues. The DMBC's accommodation of field realities through data management and biostatistics will be an important component to the effectiveness of our research.