Administrative Core

核心A管理核心 行政核心由计划主任Richard J.Whitiey博士领导。作为 负责项目资助的首席调查员，他将提供科学和 对整个项目的行政领导。G·杨西博士将协助他完成这些任务。 吉莱斯皮和詹姆斯·M·马克特，项目联席主任。这些行政核心领导人将共同努力 为该项目的所有研究项目提供集中管理支持和协作研究支持 两个机构的项目资助。此核心的目的是提供管理框架，以 促进我们的基础科学进展迅速地转化为治疗机会 对人类来说。分子病毒学、细胞生物学的交错。体外筛选、动物模型 研究和其他促进工作将由行政核心协调。行政职能部门 还包括监督所有计划项目调查员和核心人员的业务和预算问题 领袖们。将组织和协调与所有项目和核心领导的季度会议，以 确保研究活动及时进行，并确保所有计划参与者都有 非正式论坛塑造和聚焦研究活动的方向。这些会议还将加强 根据确定的优先顺序，将项目和核心活动相互集成 在每次会议上提交的结果。行政核心将协调与 外部咨询委员会，将评估个别计划项目的进展情况和 由核心提供的服务。外部咨询委员会由3名杰出的科学家组成。 病毒学家托马斯·申克博士、胶质瘤专家达雷尔·D·比格纳博士和病毒领域的领军人物罗伯特·马尔图扎博士 肿瘤溶解和临床研究。所有的努力将集中在分子上的微妙翻译上。 单纯疱疹病毒生物学和病毒-宿主细胞生物学与人类治疗的关系 恶性胶质瘤。这项计划项目拨款得到了阿拉巴马大学的全力支持 伯明翰大学和芝加哥大学。C·加里森博士的支持信(主席， UAB)，E Capiluto(教务长，UAB)，R Rich(UAB医学院院长)，E Partridge(UAB主任 癌症综合中心主任)、S·斯塔诺(儿科主任)和M·勒博( 芝加哥大学癌症中心)。 相关性(请参阅说明)：

Core A Administrative Core The Administrative Core is under the Direction of the Program Director, Dr. Richard J. Whitiey. As the responsible Principal Investigator for the Program Project Grant, he will provide the scientiflc and administrative leadership for the overall program. He will be assisted in these tasks by Drs. G. Yancey Gillespie and James M. Markert, Program Co-Directors. Together, these Administrative Core Leaders will provide centralized management support, and collaborative research support for all research projects of this two-institution Program Project Grant. The purpose of this Core is to provide the administrative framework to facilitate the rapid and expeditious translation of our basic science advances into therapeutic opportunities for humans. The interdigitation of molecular virology, cellular biology. In vitro screening, animal model studies, and other facilitating work will be coordinated by the Administrative Core. Administrative funcflons also include oversight of operations and budgetary issues for all Program Project investigators and Core Leaders. Quarterly meetings with all of the Project and Core leaders will be organized and coordinated to ensure that the research activities proceed in a timely fashion and that all program participants have an informal forum to shape and focus the direction of the research activities. These meetings will also enhance the integration of project and core activities with each other, based on priorities that are identifled from results presented at each meeting. The Administrative Core will coordinate an annual meeting with the External Advisory Committee which will evaluate the progress of the individual Program projects and the services provided by the Cores. The External Advisory Committee is compised of 3 outstanding scientists. Dr. Thomas Shenk, virologist, Dr. Darell D. Bigner, glioma expert and Dr. Robert Martuza, a leader in viral oncolysis and clinical studies. All efforts will be focused on the flmely translation of the flndings on molecular biology of herpes simplex viruses and the cellular biology of the virus-host relation to the treatment of human malignant gliomas. This program project grant has the full support of the University of Alabama at Birmingham and the University of Chicago. Letters of support appear from Drs. C Garrison (President, UAB), E Capiluto (Provost, UAB), R Rich (Dean, School of Medicine, UAB), E Partridge (Director, UAB Comprehensvive Cancer Center), S Stagno (Chair, Department of Pediatircs) and M. LeBeau (Director, The University of Chicago Cancer Center). RELEVANCE (See instructions):