MOLECULAR BIOLOGY CORE: HIV/AIDS: PUERTO RICAN, HUMAN GENETICS, ASTHMA, NEUROSCI

分子生物学核心实验室于1995年在Ponce医学院（PSM）成立。在NCRR-RCMI的持续支持下，这一核心活动在容量和用户数量上都有了巨大的增长，并对PSM人类健康和健康差异研究人员的生产力产生了切实的影响，在过去的RCMI周期中，引用我们服务的演示文稿和出版物增加了500%以上。MBCL将进入一个新的阶段，在这个竞争的更新，将继续把我们的基本使命提供访问，培训和项目开发援助的主要重点，通过促进分子生物学研究在我们目前的教师和未来的招聘工作的实施。作为下一阶段的一部分，我们的使命将扩大到更加重视服务，并将增加新的尖端技术来调节体外和体内基因表达，以补充我们现有的基因表达分析和遗传学研究能力。我们将通过四个目标来实现这些目标，简要地说：目标1 -扩大获得设备和设施的机会;目标2 -提供技术/科学支持;目标3 -为教职员工提供培训;以及目标4 -积极促进新项目的开发和新技术的使用。MBCL的所有活动将使用评估方法进行评估，以评估实现本核心目标的适用性和成功性。此外，还设计并开始实施收费制度，以便使区域协调员赞助的这项重要活动继续制度化。 公开声明 分子生物学是一个具有巨大能力的领域，可以促进我们对疾病和人类健康的科学理解。我们的核心设施提供了一个集中的专业知识来源和先进的仪器，以提高PSM科学家的生产力，使他们可以更快地做出可以转化为临床实施的发现，从而对改善美国和全球的健康产生可衡量的影响。

The Molecular Biology Core Laboratory was established in 1995 at the Ponce School of Medicine (PSM). With the continuous support of NCRR-RCMI, this Core activity has experienced tremendous growth in capacity, number of users and has tangibly impacted upon the productivity of the research faculty in human health and health disparities at PSM, with over a 500% increase in presentations and publications citing our services in the past RCMI cycle. The MBCL will enter a new phase in this competing renewal that will continue to place major emphases on our fundamental mission to provide Access, Training, and Project Development assistance by promoting the implementation of molecular biology research in the work of both our current faculty and future recruits. As part of this next phase, our mission will expand to include greater emphasis on Service and will add new cutting edge technologies to modulate gene expression both in vitro and in vivo to complement our existing capacity to perform gene expression analyses and genetics studies. We will pursue these goals via four aims, briefly: Aim 1 - To expand access to equipment and facilities; Aim 2 - To provide technical/scientific support; Aim 3 - To provide training for faculty and staff; and, Aim 4 - To actively promote the development of new projects and use of new technologies. All activities of the MBCL will be evaluated using methods to assess suitability and success in addressing the goals of this Core. In addition, a system of charge backs has been designed and begun to be implemented in order to provide for the continued institutionalization of this essential RCMI-sponsored activity. Public Statement Molecular biology is a field with tremendous capacity to advance our scientific understanding of disease and human health. Our Core facility provides a centralized source of expertise and access to sophisticated instrumentation in order to increase the productivity of the scientists at PSM so that they may more quickly make discoveries that can be translated to clinical implementation and thus have a measureable impact on improving health in the US and worldwide.