DEVELOPMENTAL PROGRAMMING: MATERNAL OBESITY AND OVER NUTRITION

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 发达国家和发展中国家都充斥着肥胖，伴随而来的是糖尿病、高血压、血管疾病等并发症。对研究与人类密切相关的模型感兴趣的研究人员将可以使用拟议的动物队列。预防、治疗和可能的治疗只能来自基础研究，这些研究是在接近人类的模型中产生和/或证实的。这项研究的目的是提高24名肥胖母亲和24名对照母亲的后代，以便在未来的其他方案中进行研究。其目的是将48名后代提高到3岁。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The developed and developing worlds are awash in obesity with the accompanying comorbidities of type" diabetes, hypertension, vascular disease etc. The proposed cohorts of animals will be available to researchers interested in studying a model that is very closely related to humans. Prevention, treatment and possible cures can only come from basic research that is generated andlor confirmed in a model close to humans. The purpose of this study is to raise 24 offspring of obese and 24 offspring control mothers to be available for study in other future protocols. The intent is to raise 48 offspring to 3 years of age.