WV-INBRE: MU & WVU BIOINFORMATICS CORE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 生物信息学核心为牵头机构和伙伴机构的研究人员提供生物信息学分析工具，并在利用这些工具进行数据分析和发现方面提供专家协助。提供Vector NTI的访问权限以进行基因序列分析。基因表达数据分析，包括免疫途径分析（IPA），与基因组学核心和非现场生成的表达结果一起提供。此外，还提供IPA访问或分析，以协助调查人员提出假设。 WV-INBRE每年夏天为合作伙伴和牵头机构的研究人员举办生物信息学研讨会。这些研讨会侧重于与WV-INBRE支持的研究项目相关的方法和技术，并由内容专家，如NIH-NCBI人员和WV-INBRE支持的软件培训人员介绍。生物信息学核心人员已在牵头机构开发了关于使用生物信息学工具的课程，并将协助伙伴机构开发课程或开展活动，以加强现有课程。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Bioinformatics Core provides investigators at the lead and partner institutions access to bioinformatics analysis tools and expert assistance in utilizing these tools for data analysis and discovery. Access to Vector NTI is provided for gene sequence analysis. Analyses of gene expression data, including Ingenuity Pathways Analysis (IPA), are provided in conjunction with the Genomics Core and for expression results generated off-site. In addition, IPA access or analyses are provided to assist investigators in generation of hypotheses. WV-INBRE sponsors a Bioinformatics Workshop every summer for investigators at the partner and lead institutions. These workshops focus on methods and techniques relevant to the research projects supported by WV-INBRE and are presented by content experts, such as NIH-NCBI personnel and training staff for software supported by WV-INBRE. Bioinformatics Core personnel have developed courses on use of bioinformatics tools at the lead institutions and will assist partner institutions in developing courses or exercises to enhance existing courses.