YOGA LIFESTYLE INTERVENTION REDUCES BLOOD PRESSURE IN HIV-INFECTED ADULTS

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 目的：HIV感染者患心血管疾病(CVD)的风险增加。降低艾滋病毒感染中心血管疾病风险的安全和有效的干预措施是高度优先事项。我们进行了一项前瞻性、随机、对照研究，以评估与匹配对照组中的护理标准治疗相比，瑜伽生活方式干预是否改善了HIV感染成年人的心血管危险因素、病毒学或免疫学状态或生活质量(QOL)。 方法：60名有轻中度心血管疾病风险的HIV感染者被分配到20周的监督瑜伽练习或标准护理治疗中。基线和第20周的测量是：胰岛素监测的2小时口服葡萄糖耐量试验，身体成分，空腹血脂/脂蛋白谱，静息血压，CD4T细胞计数和血浆HIV RNA，以及医学结果研究简表(SF)-36健康相关生活质量问卷。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. OBJECTIVE: People living with HIV infection are at increased risk for developing cardiovascular disease (CVD). Safe and effective interventions for lowering CVD risk in HIV infection are high priorities. We conducted a prospective, randomized, controlled study to evaluate whether a yoga lifestyle intervention improves CVD risk factors, virological or immunological status, or quality of life (QOL) in HIV-infected adults relative to standard of care treatment in a matched control group. METHODS: Sixty HIV-infected adults with mild-moderate CVD risk were assigned to 20 weeks of supervised yoga practice or standard of care treatment. Baseline and week 20 measures were: 2-h oral glucose tolerance test with insulin monitoring, body composition, fasting serum lipid/lipoprotein profile, resting blood pressures, CD4 T-cell count and plasma HIV RNA, and the Medical Outcomes Study Short Form (SF)-36 health-related QOL inventory.