VENTILATOR FOR MICE AND RATS TRAINING

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 弗吉尼亚大学对复制CIVM开发的小鼠和大鼠呼吸机表示了浓厚的兴趣，该呼吸机与超极化气体成像兼容。该呼吸机将为UVA带来对小鼠成像的新能力，特别是小鼠模型肺部的肿瘤生长。 该项目有四个目标： 1.为弗吉尼亚大学提供复制呼吸机硬件和软件所需的所有信息 2.在CIVM的常规成像研究期间，培训一名教师和两名学生校准呼吸机和给小鼠通气。无需对UVA进行专门的成像研究。相反，UVA将加入在中心安排的现有会话 3.在UVA组装双呼吸机期间提供技术指导 4.在UVA使用呼吸机准备首次成像研究时提供指导，并就解决最初几次研究中出现的缺陷提供建议。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The University of Virginia has expressed a vigorous interest at duplicating the ventilator for mice and rats developped at the CIVM, compatible with hyperpolarized gas imaging. The ventilator will bring UVA the new capability to image mice, specifically tumor growth in the lungs of a mouse model. The project has four goals: 1. Supply the University of Virginia with all the information necessary to duplicate the ventilator hardware and software 2. Train one faculty and two students at calibrating the ventilator and ventilating a mouse during a routine imaging study at the CIVM. It will not be necessary to conduct a dedicated imaging study for UVA. Rather, UVA will join an existing session scheduled at the Center 3. Provide technical guidance during the assembly of the duplicate ventilator at UVA 4. Provide guidance in preparation of the first imaging studies at UVA using the ventilator, and advice on resolving shortcomings appearing during the first few studies.