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中文摘要
翻译
临床转化信息学和生物储存库核心(CTIBC)将作为临床数据和生物标本(包括从血友病A患者中采集的血浆和DNA)的中央储存库。 CTIBC将作为协调临床数据以及血浆和DNA的收集和储存的资源,以支持项目3的目标3和项目4的目标1和2。此外,CTIBC将作为培训核心的主要资源,作为与生物标本相关的临床数据来源,可供学员和年轻研究人员用于止血方面的新临床转化研究项目。具有高 与生物样本相关的高质量前瞻性收集数据将为参加KL-2指导临床研究学者计划或临床研究硕士课程的学员进行临床转化研究提供丰富的机会。
英文摘要
The Clinical-Translational Informatics and Biorepository Core (CTIBC) will serve as a central repository of clinical data and biological specimens, including plasma and DNA collected from patients with hemophilia A. The CTIBC will serve as a resource to coordinate collection and storage of clinical data as well as plasma and DNA to support project 3 aim 3 and project 4 aim 1 and 2. Additionally, the CTIBC will serve as a major resource for the training core as a source of clinical data linked to biological specimens that can be used by trainees and young investigators for new clinical-translational research projects in hemostasis. Having high quality prospectively collected data linked to biological samples will provide a wealth of opportunity for clinical translational research performed by trainees participating in either the KL-2 Mentored Clinical Research Scholars Program or Master of Science in Clinical Research program.
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Unraveling the immune response to factor VIII
  • 批准号:
    10406900
  • 项目类别:
  • 资助金额:
    $161.33万
  • 财政年份:
    2018
  • 负责人:
    John S. Lollar
  • 依托单位:
The Structural Basis for the Immune Recognition of Factor VIII
  • 批准号:
    10406902
  • 项目类别:
  • 资助金额:
    $38.16万
  • 财政年份:
    2018
  • 负责人:
    John S. Lollar
  • 依托单位:
Unraveling the immune response to factor VIII
  • 批准号:
    9522256
  • 项目类别:
  • 资助金额:
    $164.03万
  • 财政年份:
    2018
  • 负责人:
    John S. Lollar
  • 依托单位:
Novel Assays Predicting Phenotypic Heterogeneity in Severe Hemophilia
  • 批准号:
    8464235
  • 项目类别:
  • 资助金额:
    $49.64万
  • 财政年份:
    2013
  • 负责人:
    John S. Lollar
  • 依托单位:
海外基金