Immunology Research Training Program

描述（由申请人提供）：在本申请中，我们寻求对加州大学欧文分校（UCI）免疫学研究培训计划的重新支持。通过最初的奖项，免疫学研究培训计划的目标是培训科学家研究免疫系统及其在自身免疫、感染和癌症中的作用。这些研究领域由UCI免疫学研究所（IFI）的30名教师负责，在Paolo Casali博士的领导下，将为该培训计划提供行政和学术核心。IFI教师将利用现有的综合/伞细胞和分子生物科学（CMB）研究生课程的优势，制定一个充满活力的培训计划。UCI免疫学研究培训计划的优势包括：1）IFI提供的高度结构化的培训计划和强大的科学环境; 2）项目主任/PI，IFI创始人Paolo Casali博士的领导和经验，以及纽约州威尔康奈尔医学院NIH T32支持的免疫学项目的前主任（1999-2003）; 3）的Preceptors/导师是建立在广泛的免疫学领域的研究人员; 4）现有的博士前学员，从顶级机构招募，免疫学研究培训计划的成功，在其存在的第一个四年招募和吸引来自不同人群的个人; 5）UCI免疫学研究培训计划在其存在的前四年中有着良好的培训记录，在此期间，9名博士前学员和2名博士后学员得到了支持，并取得了很高的成效。在第二个支持期（2010-2015年），每年为6名预博士寻求资金，以容纳我们庞大的招聘库中更多高素质的预博士。重要的是，UCI的研究生部也将在资助此申请时提供1个额外的名额;因此，有可能为7名博士前学生提供免疫学研究的支持。UCI在免疫学方面的现有优势将通过拟议的培训计划得到加强，并将促进该机构的长期使命，即培养生物医学科学方面的高素质研究生。 相关性：免疫学的核心是一门学科，掌握着解开人类一些最致命和最令人衰弱的疾病的钥匙。UCI的免疫学研究培训计划旨在培养和发展下一代杰出的免疫学家，科学家将站在发现和应用免疫系统知识以改善人类疾病的最前沿。

DESCRIPTION (provided by applicant): In the present application, we seek renewed support for the Immunology Research Training Program at the University of California, Irvine (UCI). Made possible through the initial award, the objective of the Immunology Research Training Program is to train scientists to study the immune system and its role in autoimmunity, infection and cancer. These research areas are addressed by the 30 faculty of the UCI Institute for Immunology (IFI), which, under the leadership of Dr. Paolo Casali, will provide the administrative and academic core for this training program. The IFI faculty will capitalize on the strengths of the existing integrated/umbrella Cellular and Molecular Biosciences (CMB) graduate program to articulate a vibrant training program. The strengths of the UCI Immunology Research Training Program include: 1) The highly structured training program and scientifically strong environment emanating from the IFI; 2) The leadership and experience of the Program Director/PI, Dr. Paolo Casali, founder of the IFI, and former director of the NIH T32-supported Immunology Program at Weill Cornell Medical College, NY (1999-2003); 3) the Preceptors/Mentors are established investigators in wide-ranging areas of immunology; 4) the existing pool of predoctoral trainees, recruited from top-tier institutions, and the success of the Immunology Research Training Program in its first four years of existence in recruiting and attracting individuals from diverse populations; 5) The strong training record of UCI Immunology Research Training Program in its first four years of existence, during which 9 pre-doctoral trainees and 2 postdoctoral trainees were supported and have been highly productive. For this second period of support (2010-2015), funding is sought for 6 pre-docs per year to accommodate more highly qualified predocs from our large recruitment pool. Importantly, the Graduate Division at UCI will also provide 1 additional slot upon funding of this application; thus, there is potential for 7 pre-doctoral students to be supported for immunology research. The existing strengths in immunology at UCI will be embellished through the proposed training program, and will promote the institution's long-standing mission to educate highly qualified graduate students in biomedical sciences. RELEVANCE: Immunology is at its core a discipline that holds the keys to unlock some of humankind's most deadly and debilitating ailments. The Immunology Research Training Program at UCI seeks to train and develop the next generation of outstanding immunologists, scientists who will be at the forefront of discovery and application of knowledge about the immune system to ameliorate human disease.