Immunology Research Training Program

描述(由申请人提供)：在本申请中，我们为加州大学欧文分校(UCI)的免疫学研究培训计划寻求新的支持。通过最初的奖项，免疫学研究培训计划的目标是培训科学家研究免疫系统及其在自身免疫、感染和癌症中的作用。这些研究领域由UCI免疫学研究所(IFI)的30名教员负责，该研究所在Paolo Casali博士的领导下，将为本培训计划提供行政和学术核心。IFI的教师将利用现有综合/伞式细胞和分子生物科学(CMB)研究生课程的优势，阐明一个充满活力的培训计划。UCI免疫学研究培训计划的优势包括：1)来自IFI的高度结构化的培训计划和强大的科学环境；2)IFI计划主任/PI、IFI创始人Paolo Casali博士和纽约州威尔·康奈尔医学院NIH T32支持的免疫学计划的前主任Paolo Casali博士的领导和经验(1999-2003年)；3)PReceptor/导师是免疫学广泛领域的知名研究人员；4)现有的博士前培训生人才库，从一流机构招聘，免疫学研究培训计划在存在的最初四年中成功地从不同人群中招募和吸引个人；5)UCI免疫学研究培训计划成立头四年的良好培训记录，在此期间，9名博士后学员和2名博士后学员得到了支持，并取得了很高的成效。在第二个支助期(2010-2015年)，每年为6名博士生寻求资金，以便从我们庞大的招聘人才库中招收更多高素质的博士生。重要的是，UCI研究生部还将在资助这一申请时提供1个额外的名额；因此，有7名博士前学生有可能获得免疫学研究的支持。UCI在免疫学方面的现有优势将通过拟议的培训计划得到加强，并将促进该机构培养高素质生物医学研究生的长期使命。 相关性：免疫学的核心是一门学科，它掌握着解开人类一些最致命和最虚弱的疾病的钥匙。UCI的免疫学研究培训计划旨在培养和发展下一代杰出的免疫学家，他们将站在发现和应用有关免疫系统的知识以改善人类疾病的前沿。

DESCRIPTION (provided by applicant): In the present application, we seek renewed support for the Immunology Research Training Program at the University of California, Irvine (UCI). Made possible through the initial award, the objective of the Immunology Research Training Program is to train scientists to study the immune system and its role in autoimmunity, infection and cancer. These research areas are addressed by the 30 faculty of the UCI Institute for Immunology (IFI), which, under the leadership of Dr. Paolo Casali, will provide the administrative and academic core for this training program. The IFI faculty will capitalize on the strengths of the existing integrated/umbrella Cellular and Molecular Biosciences (CMB) graduate program to articulate a vibrant training program. The strengths of the UCI Immunology Research Training Program include: 1) The highly structured training program and scientifically strong environment emanating from the IFI; 2) The leadership and experience of the Program Director/PI, Dr. Paolo Casali, founder of the IFI, and former director of the NIH T32-supported Immunology Program at Weill Cornell Medical College, NY (1999-2003); 3) the Preceptors/Mentors are established investigators in wide-ranging areas of immunology; 4) the existing pool of predoctoral trainees, recruited from top-tier institutions, and the success of the Immunology Research Training Program in its first four years of existence in recruiting and attracting individuals from diverse populations; 5) The strong training record of UCI Immunology Research Training Program in its first four years of existence, during which 9 pre-doctoral trainees and 2 postdoctoral trainees were supported and have been highly productive. For this second period of support (2010-2015), funding is sought for 6 pre-docs per year to accommodate more highly qualified predocs from our large recruitment pool. Importantly, the Graduate Division at UCI will also provide 1 additional slot upon funding of this application; thus, there is potential for 7 pre-doctoral students to be supported for immunology research. The existing strengths in immunology at UCI will be embellished through the proposed training program, and will promote the institution's long-standing mission to educate highly qualified graduate students in biomedical sciences. RELEVANCE: Immunology is at its core a discipline that holds the keys to unlock some of humankind's most deadly and debilitating ailments. The Immunology Research Training Program at UCI seeks to train and develop the next generation of outstanding immunologists, scientists who will be at the forefront of discovery and application of knowledge about the immune system to ameliorate human disease.