Epithelial Physiology and Cell Biology Workshop at the Telluride Science Res Ctr

描述（由申请人提供）：通过将上皮运输和离子通道/转运体细胞信号调节的不同专业知识的研究人员与专注于疾病过程的临床医生聚集在一起，上皮生理学和细胞生物学研讨会促进了合作并催化了科学进步，正如之前会议的成功所例证的那样。该研讨会每年（自2004年以来）在科罗拉多州特柳赖德举行，由特柳赖德科学研究中心提供后勤会议支持。该主题的前沿性质反映在联合组织者，博士。John Cuppoletti, My N. Helms, Thomas Kleyman, Peter Snyder，以及许多演讲者。主题将包括（但不限于）自由基在离子运输中的作用，基于酸感应离子通道的x射线晶体结构的钠通道分子模型，以及基于prostone的化合物靶向氯通道的潜在用途。此外，还将设立“研究认可旅游奖”，鼓励初级研究人员参与研讨会。

DESCRIPTION (provided by applicant): By bringing together investigators with varied expertise in epithelial transport and cell signaling regulation of ion channels/transporters with clinicians focused on disease processes, the Epithelial Physiology and Cell Biology Workshop stimulates collaborations and catalyzes scientific progress , as has been exemplified by the successes of the previous meetings. This workshop is held annually (since 2004) in Telluride, Colorado with logistical meeting support provided by the Telluride Science Research Center. The cutting edge nature of the topics to be presented is reflected in the co-organizers, Drs. John Cuppoletti, My N. Helms, Thomas Kleyman, Peter Snyder, and a diverse range of speakers. Topics will include (but is not limited to) the role of free radicals in ion transport, molecular modeling of sodium channels based on the X-ray crystal structure of acid sensing ion channels, and the potential use of prostone based compounds to target chloride channels. Participation by junior researchers in this workshop will also be enhanced through a proposed Research Recognition Travel Award. PUBLIC HEALTH RELEVANCE: The annual Epithelial Physiology and Cell Biology Workshop, held in conjunction with the Telluride Science Research Center, sets new direction for scientific research. The Principal Investigator, together with Drs. Kleyman, Cuppoletti, and Snyder requests R13 funds that will defray the cost of travel for trainees who wish to attend this scientific workshop.