Advances in Optics for Biotechnology, Medicine and Surgery

描述（由申请人提供）：该提案要求资金支持“生物技术，医学和外科光学进展”，这是一个跨学科会议，最适合交叉施肥（约120名与会者），专注于生物医学光学领域。 生物医学光学是指在医学和生物医学研究中使用光，并利用组织和从紫外到红外波长的光之间可能发生的许多相互作用。这个年轻的领域所涵盖的广泛技术对医学诊断和治疗以及生物医学研究产生了深远的影响。水对光的吸收是激光手术的基础。其他组织对光线的吸收 还利用氧合血红蛋白和脱氧血红蛋白等成分进行光谱学和成像，以评估组织功能和灌注。内在荧光团，包括一系列蛋白质和代谢物，也可以用于体内疾病诊断。各种外源性光学成像造影剂也在开发中，其中许多利用了基因组学和蛋白质组学的最新进展用于分子靶向。这些新的光学技术共同实现了从整个头部或乳房到单个细胞或亚细胞成分的长度尺度成像。利用其他类型的光-组织相互作用（如光声）的新的光谱学和成像技术也在探索中。这项工作涵盖了广泛的学科，包括工程，物理，数学和计算，并需要广泛的技能集，结合联合收割机这些技术领域与临床医学和基础生物医学研究的深刻理解。本次会议将汇集来自生物医学光学研究各个方面的专家，包括临床医生和行业专家。会议形式旨在促进医学，科学和工程等广泛领域的创造性想法的分享，同时为学生，学员和年轻的研究人员提供充分的机会，使他们的知识多样化，并与该领域的主要领导人建立关系。会议将于2013年6月2日至5日在加利福尼亚州太浩湖的Granlibakken会议中心和旅馆举行。会议将由会议主席的现场概述和邀请有成就的高级或正在崛起的年轻研究人员的演讲组成，他们将定义当前的技术水平，并提出新的和有前途的研究方向。海报会议和“热门话题”口头报告会议将为研究生和博士后学员提供展示自己研究的机会，并从临床医生、其他科学家和工程师以及行业和政府代表那里获得直接反馈。因此，本次会议的目的是：目标1，确定生物医学光学领域的最新和最前沿的发展，并提供一个分享这些新发现和想法的论坛;目标2，纳入对该领域具有根本重要性的主题，以促进跨学科的学习和培训，并确定有前途的模式朝着更广泛的采用/商业化的进展;目标3，创造一个促进网络、思想交流、协作、指导和跨学科学习的环境;和目标4，通过鼓励研究生、博士后实习生、年轻研究人员和代表性不足群体的成员出席和参与，确保演讲者和与会者的多样性，以便所有有能力为会议作出贡献并从中获益的人都有机会参加会议并展示其工作。

DESCRIPTION (provided by applicant): This proposal is requesting funds to support "Advances in Optics for Biotechnology, Medicine and Surgery", an interdisciplinary conference, optimally sized for cross-fertilization (~120 attendee), focused on the field of biomedical optics. Biomedical optics refers to the use of light in medicine and biomedical research, and exploits the many interactions that can occur between tissue and light from ultra-violet to infra-red wavelengths. The broad range of techniques encompassed by this young field is having a profound impact on medical diagnostics and therapy, as well as in biomedical research. Absorption of light by water is the basis of laser surgery. The absorption of light by other tissue constituents, such as oxy- and deoxy-hemoglobin, is also being harnessed to perform optical spectroscopy and imaging that can be used to evaluate tissue function and perfusion. Intrinsic fluorophores, including a range of proteins and metabolites, can also be exploited for disease diagnosis in vivo. A wide range of exogenous optical imaging contrast agents are also in development, many of which take advantage of recent advances in genomics and proteomics for molecular targeting. Together these new optical technologies enable imaging over length-scales from the whole head or breast, to single cells or sub-cellular components. New optical spectroscopy and imaging technologies that exploit other types of light-tissue interactions (e.g. photo acoustics) are also being explored. This work encompasses a wide range of disciplines including engineering, physics, and mathematics and computing, and requires broad skills sets that combine these technical areas with a deep understanding of clinical medicine and basic biomedical research. This meeting will draw together experts from all facets of biomedical optics research, including clinicians and experts from industry. The conference format is designed to stimulate the sharing of creative ideas across broad areas of medicine, science and engineering, while providing ample opportunities for students, trainees and young investigators to diversify their knowledge and develop relationships with key leaders in the field. The conference will be held June 2-5, 2013 at the Granlibakken Conference Center and Lodge, Lake Tahoe, CA. Sessions will be composed of field overviews by the session chairs and invited talks from accomplished senior or rising young investigators, who will define the current state of the art and suggest new and promising research directions. A poster session and 'hot topics' oral presentation session will provide graduate students and postdoctoral trainees the opportunity to present their own research and get direct feedback from clinicians, other scientists and engineers, and industry and government representatives. The aims of this meeting are therefore: Aim 1, to identify the newest and most cutting edge developments in the field of biomedical optics, and provide a forum for sharing these new discoveries and ideas; Aim 2, to incorporate topics of fundamental importance to the field to facilitate interdisciplinary learning and training, and to ascertain the progress of promising modalities towards wider adoption/commercialization; Aim 3, to create an environment that stimulates networking, exchange of ideas, collaboration, mentoring and cross-disciplinary learning; and Aim 4, to ensure diversity in both speakers and attendees, by encouraging the attendance and participation of graduate students, post-doctoral trainees, young investigators and members of underrepresented groups, so that all who have the capacity to contribute to and gain from the meeting are afforded the opportunity to attend and showcase their work.