Chemistry Biology Interface Training Program

描述（由申请人提供）：这是加州大学洛杉矶分校化学-生物学界面博士前培训计划的第三次更新申请，该计划自1993年以来一直得到资助。参加培训的学员来自化学、生物化学系和生物化学系的各个学科；医学、微生物学、免疫学和分子遗传学；分子、细胞和发育生物学；分子和医学药理学和生理学。其他培训教师来自微生物学和分子遗传学，血液学/肿瘤学部门。研究生实习生参与的研究(1)具有很强的化学和/或结构成分，(2)与解决化学/生物学界面的重大未解决问题相关。这个连贯和互动的培训项目大大加强了加州大学洛杉矶分校在分子和生命科学方面的科学和教育环境。该计划对化学和生物化学系产生了很大的影响，促进了追求生物有机、生物无机和生物物理化学职业的博士生的教育和培训，并教授了他们在现代分子生物学中取得成功所需的技能。该计划教育生物学家在最先进的化学方法和仪器。培训计划提供跨学科的博士前研究培训，应用化学概念和工具来解决现代生物学中的问题。本课程的主要要求是：(1)完成化学205（一门跨学科的研究生水平课程，名为“生物化学导论”），化学205B（培训教师对其方法的介绍），化学203B（道德培训）；(2)参加每周一次为期一年的研讨会课程，“生物化学研讨会”，化学206，由入学学生和教师的研究报告组成，并伴有对所提出主题的深入讨论；(3)参加跨学科的科研实习。外部演讲者就化学/生物界面的主题进行研究研讨会。相关性：加州大学洛杉矶分校化学-生物学界面培训计划培养攻读博士学位的科学家，将最先进的化学研究工具应用于生物学问题。该计划的毕业生将成为解决生物医学研究问题的主要研究人员，并将发展对美国医学研究和健康的理解和技能。

DESCRIPTION (provided by applicant): This is the application for the third renewal of the UCLA Chemistry-Biology Interface Predoctoral Training Program, which has now been funded since 1993. Participating trainees have come from all divisions of Chemistry and Biochemistry, as well as the Departments of Biological Chemistry; Medicine, Microbiology, Immunology, and Molecular Genetics; Molecular, Cell, and Developmental Biology; Molecular and Medical Pharmacology, and Physiology. Additional training faculty comes from the Departments of Microbiology and Molecular Genetics, and Hematology/Oncology. Graduate student trainees are involved in research that (1) has strong chemical and/or structural components and (2) are relevant to addressing significant unsolved problems at the chemistry/biology interface. This coherent and interactive training program has significantly strengthened the scientific and educational environment at UCLA in the molecular and life sciences. The program has had a high impact on the Department of Chemistry and Biochemistry by promoting the education and training of predoctoral students pursuing careers in bioorganic, bioinorganic, and biophysical chemistry, and by teaching the skills they need to succeed in modern molecular biology. The program educates biologists in state-of-the-art chemical methods and instrumentation. The training program provides interdisciplinary predoctoral research training in applications of chemical concepts and tools to the solution of problems in modern biology. The major requirements of our program are (1) completion of Chem. 205, an interdisciplinary graduate level course entitled "Introduction to the Chemistry of Biology," Chem. 205B, presentations by training faculty on their methods, and Chem. 203B, ethics training; (2) participation in a weekly year-long seminar course, "Seminar in Chemistry of Biology," Chem. 206, consisting of research presentations by the enrolled students and by faculty, accompanied by intensive discussion of the topics presented; and (3) participation in cross-disciplinary research internships. Outside speakers give research seminars on topics at the chemistry/biology interface. RELEVANCE: The UCLA Chemistry-Biology Interface Training Program trains scientists working for the Ph.D. to apply State-of-the-art tools of chemical research to biological problems. The graduates of this program become leading researchers in the solution of problems of biomedical research and will develop understanding and skills that will advance medical research and health in the United States.