Computer Aided Detection of Diabetic Retinopathy in Veterans with Diabetes

项目叙事 糖尿病视网膜病变是糖尿病的一种可怕的并发症，也是退伍军人失明的重要原因。这个 弗吉尼亚州通过护理协调办公室，一直在迅速采取行动，为所有退伍军人进行远程筛查 对于糖尿病，使用数码相机和经过认证的独立执业医生作为读者。专家阅读 受制于观察者内部和观察者之间的可靠性，专家阅读器稀缺、昂贵且周转率高 费率。计算机检测具有提高成本效益、可扩展性和可持续性的潜力 电视成像程序，同时为阅读过程增加了一个强大的维度。然而，仍有遗迹 科学界的Scepsis和自动病变检测尚未在临床实践中得到证实。我们会 比较人类专家、计算机辅助人类专家和独立计算机在 敏感度、特异度、诊断时间，并对自动化病变和 在一项对大量退伍军人进行的前瞻性临床试验中检测糖尿病视网膜病变。 阿布拉莫夫博士是爱荷华大学眼科副教授，也是研究 开发用于评估视网膜疾病的自动化系统。他已经组建了一个专家小组来协助 这项工作包括眼科医生、生物统计学家和远程医疗专家。 3.

Project Narrative Diabetic retinopathy is a feared complication of diabetes and an important cause of blindness in veterans. The VA, through the Office of Care Coordination, has been rapidly moving to teleretinal screening for all veterans with diabetes, using digital cameras and certified independent licensed practitioners as readers. Expert reading suffers from intra-and interobserver reliability, and expert readers are scarce, costly and have high turnover rate. Computer detection has the potential to increase the cost-effectiveness, scalability and sustainability of teleretinal imaging programs while adding a strong dimension to the reading process. However, there remains scepsis within the scientific community and automated lesion detection is unproven in clinical practice. We will compare the performance of human experts, human experts aided by computer and standalone computer on sensitivity, specificity, time to diagnosis, and perform a cost-effectiveness analysis on automated lesion and diabetic retinopathy detection in a prospective clinical trial on a large number of veterans. Dr. Abramoff is Associate Professor of Ophthalmology at the University of Iowa, and is a leader in studies to develop automated systems for evaluation of retinal disease. He has assembled an expert team to assist in this effort, including ophthalmologists, biostatisticians, and experts in telemedicine. 3