Center for Molecular & Cellular Studies of Ped Disease

描述（由申请人提供）：杜克大学医学中心儿科CHRCDA项目旨在培养成熟的儿科初级教师成为独立的医师-科学家，他们熟练掌握尖端的实验室研究方法，并追求长期的学术生涯，研究与儿童疾病相关的重要问题。这个项目是基于一个优秀的候选人池，一个强大的教学课程，经验丰富的导师谁执行最先进的实验室研究，以及一个良好的研究环境。首席研究员/项目主任和培训主任将得到内部顾问委员会和外部顾问委员会的协助，以选择学者，审查学者的进展，并确保项目的最佳运作。每年将支持四名学者，他们将从儿科的初级教师中挑选，特别强调招募妇女和代表性不足的少数民族。该项目师资队伍将来自四个广泛定义的研究领域，即发育生物学、细胞生物学和细胞信号传导、感染和免疫、遗传学、基因组学和代谢组学。项目教师将包括来自儿科和杜克大学医学中心其他部门的导师，在所有情况下，他们在研究、资助和指导方面都有良好的记录。教学课程将补充实验室研究经验，包括四讲的写作课程和五讲的负责任的研究行为课程。这些学者将可以使用杜克大学的所有共享研究设施，包括nci资助的综合癌症中心、杜克基因组科学与政策研究所、杜克人类基因组变异中心、杜克人类疾病建模中心、杜克人类疫苗研究所和杜克转化医学研究所等核心设施。

DESCRIPTION (provided by applicant): The CHRCDA Program in the Department of Pediatrics at Duke University Medical Center is intended to foster the maturation of pediatric junior faculty into independent physician-scientists who are skilled in cutting-edge methods of laboratory research and who pursue long-term academic careers investigating important issues related to childhood diseases. This Program is based on a pool of outstanding candidates, a strong curriculum of didactic courses, experienced mentors who perform state-of-the-art laboratory research, and an excellent research environment. The Principal Investigator/Program Director and the Training Director will receive assistance from an Internal Advisory Board and an External Advisory Board in selecting scholars, reviewing the progress of scholars, and ensuring the optimal operation of the program. Four scholars will be supported each year and will be drawn from junior faculty in the Department of Pediatrics, with particular emphasis on recruitment of women and underrepresented minorities. The Program Faculty will be drawn from four broadly defined areas of research excellence, namely Developmental Biology, Cell Biology and Cell Signaling, Infection and Immunity, and Genetics, Genomics, and Metabolomics. The Program Faculty will include mentors from the Department of Pediatrics and from other departments at Duke University Medical Center, in all cases characterized by a strong track record in research, funding, and mentoring. Didactic courses will complement the laboratory research experiences and will include a four-lecture course on writing and a five-lecture course on Responsible Conduct of Research. The scholars will have access to all of the shared research facilities at Duke University, including core facilities of the NCI-funded Comprehensive Cancer Center, the Duke Institute for Genome Sciences and Policy, the Duke Center for Human Genome Variation, the Duke Center for Human Disease Modeling, the Duke Human Vaccine Institute, and the Duke Translational Medicine Institute, among others.