Southeast Cancer Control Consortium, Inc

描述(申请人提供)：东南癌症控制联盟公司(SCCC)，CCOP自1987年以来一直由国家癌症研究所(NCI)资助。SCCC是由20个组成部分/24个机构组成的联合体，位于东南部的五个州地区。SCCC的长期目标是将最先进的临床试验带到社区机构的竞技场，以增加获得机会。据估计，转诊社区的覆盖面为840万，人口结构反映出人口密度低，社会经济和教育发展有限，女性比例超过50%，非裔美国人与白人人口的比例几乎是全国平均水平的两倍。共有155名医生参加。每个组成部分都有一名指定的“社区领袖”(CL)和“研究协调员”(SC)，负责协调参与计划的医生和研究团队。研究团队由肿瘤学护士和临床研究助理(CRA)组成，他们是由SCCC运营办公室按照联邦和研究基地(RB)法规培训的。SCCC业务办公室通过以下方式协调各项活动：电话/传真/电子邮件信息；为苏格兰皇家银行提供文件和查询的网站；监测机构审查委员会(IRB)的批准情况；RB协议半月一次的邮寄；进行组成部分的现场访问；数据管理培训/继续教育方案；编写赠款申请和报告；以及协调RB审计。SCCC运营办公室为这些组件提供来自8家RBS的临床试验。每个组成部分确定适用于其区域的研究，由人类研究保护办公室(OHRP)授权的当地IRB批准。CLS和SCS对试行进行教育和促进。这个庞大的网络为医生提供了获得最先进水平的癌症计划的机会，因此患者/参与者可以获得当前的选择。其目标是通过增加参与癌症研究的医生数量来克服参与临床试验的种族、少数民族、性别和社会经济障碍，从而降低癌症的发病率和死亡率，符合方案指南的要求。

DESCRIPTION (provided by applicant): The Southeast Cancer Control Consortium, Inc. (SCCC), CCOP has been funded by the National Cancer Institute (NCI) since 1987. The SCCC is a consortium of 20 components/24 institutions in a five-state area of the southeast. The SCCC's long-term objective is to bring state-of-the-art clinical trials to an arena of community institutions to increase access. The catchment of the referral communities is estimated at 8.4 million, with demographics reflecting a low population density, limited socioeconomic and educational development, female percentage greater than 50%, and ratio of African American to white population almost twice the national average. There are 155 participating physicians. Each component has a designated "Community Leader" (CL) and "Study Coordinator" (SC) responsible for coordination of the program among participating physicians and the research team. The research team is comprised of oncology nurses and clinical research associates (CRAs) trained by the SCCC Operations Office in compliance to federal and research base (RB) regulations. The SCCC Operations Office coordinates the activities by providing: telephone/fax/email information; website that supplies documents and queries for RBs; Institutional Review Board (IRB) approvals monitoring; RB protocol semimonthly mailings; conduction of component on-site visits; data management training/continuing education programs; preparation of grant applications and reports; and coordination of RB audits. The SCCC Operations Office provides the components with clinical trials from eight RBs. Each component determines the studies applicable to their area and the local IRB, which is authorized by the Office for Human Research Protections (OHRP), grants approval. The CLs and SCs educate and facilitate trial implementation. The expansive network supplies physicians' access to the most advanced level of cancer programs, so patients/participants may access current options. The goal is to reduce morbidity and mortality of cancer by overcoming ethnic, minority, gender, and socioeconomic barriers to clinical trial participation through increasing the number of physicians participating in cancer research with compliance maintained in protocol guidelines.