Environmental Statistics and Biostatistics Core

环境统计学与生物信息学核心 摘要 环境统计和生物信息学核心(ESBC)提供了广泛的 支持生物统计学、统计遗传学和基因组学、生物信息学和数据科学 与哈佛大学陈-尼赫斯环境中心有关的调查人员 健康。还在其他几个专门领域提供援助，包括 环境流行病学与时空分布的统计建模 引用的数据。除了设计和分析支持外，核心教职员工还提供建议 关于可复制的原理以及统计和计算工具的调查人员 科学，包括数据管理、大规模研究计算基础设施和 分析管道。此外，核心成员还为教职员工、研究生提供统计培训 学生和从事中心相关项目的研究员。核心教职员工和研究人员 参与与任务相关的方法论研究，以问题和 方法上的挑战，向中心成员和 更广泛的环境卫生社区。拥有这一核心使我们能够提供 与环境健康问题特别相关的专门服务，例如 统计基因组学和生物信息学。它还为我们提供了必要的支持，使我们能够 提供教育活动，如与(初级)调查人员1：1单独会面， 集中工作组解决共同问题，并举办相关研讨会。 我们能够利用我们的中心支持和大学资源最大限度地利用我们的 为中心成员提供服务。

ENIRONMENTAL STATISTICS AND BIOINFORMATICS CORE ABSTRACT The Environmental Statistics and Bioinformatics Core (ESBC) provides a wide range of support in biostatistics, statistical genetics and genomics, bioinformatics, and data science for investigators associated with the Harvard Chan-NIEHS Center for Environmental Health. Assistance is also available in several other specialized areas including environmental epidemiology and statistical modeling of spatially and temporally referenced data. In addition to design and analysis support, Core faculty and staff advise investigators on principles as well as statistical and computational tools for reproducible science, including data management, large-scale research computing infrastructure, and analysis pipelines. Further, Core members provide statistical training for faculty, graduate students, and fellows working on Center-related projects. Core faculty and researchers engage in mission-related methodological research motivated by questions and methodological challenges, providing freely available software to Center members and the broader environmental health community. Having this Core enables us to provide specialized services particularly relevant to environmental health issues, such as statistical genomics and bioinformatics. It also gives us the necessary support to be able to offer educational activities such as 1:1 individual meetings with (junior) investigators, focused working groups that tackle common problems, and holding relevant seminars. We are able to leverage our Center support with University resources to maximize our services to Center members.