Biostatistics and Patient Registry Core

生物统计和患者登记核心提供统计协作和数据管理支持 对于每个孢子项目、核心、发展研究项目和职业 发展奖获得者。支助领域包括制定统计设计和分析计划， 质量控制、数据库开发、数据表格开发和处理、数据收集和录入、 数据分析和解释、手稿准备和数据归档。生物统计学与患者 注册中心将继续监督乳腺癌的发展、人口和维持 病人登记处(BCPR)。生物统计和患者登记核心的成员将继续合作 与梅奥基金会的工作人员合作，他们正在进行一项企业范围的计划，以开发虚拟数据 整合了Mayo电子病历元素的仓库。手术指数、病理指数。 肿瘤登记处、组织登记处、癌症中心数据库、订单和资源利用数据库。这些 合作将导致一种手段，为乳腺癌孢子项目确定患者队列，并 将一些元素以电子方式填充到BCPR中。 在上一个供资期间，核心采用并调整了久经考验的程序和 由生物医学统计和信息学司开发的系统，该司是最大的统计小组之一 在乡下。乳腺癌患者登记处(BCPR)是从一个单一的研究数据库发展而来的，该数据库包含 将人口统计和结果数据存储到数据库中，该数据库能够存储各种患者队列的数据 公共数据元素和研究特定数据元素。BCPR数据不仅被 孢子调查员，但预定义的患者队列已与DCIS协作中心共享 乳腺癌协会联合会，乳腺癌改良剂研究人员联合会 BRCAI/2和癌症基因组图谱。 核心成员参加了项目会议，并与项目进行了一对一的会议 团队成员讨论统计设计、分析计划、新出现的研究问题和可能的 未来方向；数据分析和解释，以及手稿起草。这些合作 已经出版了29本出版物，有助于我们了解乳腺癌的发展、风险 和管理。

The Biostatistics and Patient Registry Core provides statistical collaboration and data management support for each of the SPORE projects, the Cores, the Developmental Research Projects and the Career Development Awardees. Areas of support include development of a statistical design and analysis plan, quality control, database development, data form development and processing, data collection and entry, data analysis and interpretation, manuscript preparation, and data archiving. The Biostatistics and Patient Registry Core will continue to oversee the development, population, and maintenance of the Breast Cancer Patient Registry (BCPR). Members of the Biostatistics and Patient Registry Core will continue collaborations with the Mayo Foundation staff who are working on an enterprise-wide initiative to develop a virtual data warehouse that integrates elements of the Mayo electronic medical record. Surgical Index, Pathology index. Tumor Registry, Tissue Registry, Cancer Center database, orders, and resource utilization database. These collaborations will lead to a means to identify patient cohorts for Breast Cancer SPORE projects and to electronically populate some elements into the BCPR. During the previous funding period, the Core has employed and adapted the time-tested procedures and systems developed by Division of Biomedical Statistics and Informatics, one of the largest statistical groups in the country. The Breast Cancer Patient Registry (BCPR) grew from a single study database containing demographic and outcome data to a database capable of storing data on a variety of patient cohorts using both common data elements and study specific data elements. Not only has the BCPR data been utilized by SPORE investigators but pre-defined patient cohorts have been shared with the DCIS Collaborative Consortium, Breast Cancer Association Consortium, the Consortium of Investigators of Modifiers of BRCAI/2, and The Cancer Genome Atlas. Core members have participated in Project meetings as well as have held one on one meetings with Project team members to discuss statistical designs, analysis plans, emerging research questions and possible future directions; data analysis and interpretation, and the drafting of manuscripts. These collaborations have led to 29 publications that have contributed to our understanding of breast cancer development, risk and management.