Fogarty HIV Research Training Program for Low and Middle-Income Countries

项目摘要 这项建议的重点是在博茨瓦纳进行预防研究，以减少艾滋病毒/艾滋病的发病率。这是 中心的教师导师，谁与对方广泛合作， 与博茨瓦纳的主要合作伙伴合作。我们的培训合作伙伴是博茨瓦纳哈佛艾滋病研究所 伙伴关系（BHP），博茨瓦纳卫生部（MOH）的有限责任非营利公司（LLC）。 BHP是博茨瓦纳最大的艾滋病毒/艾滋病研究组织，也是非洲最大的研究组织之一。很长的- 本培训计划的长期目标和目的是培养能够承担以下责任的研究领导者： 在未来5-10年内，为卫生部配备当地艾滋病专家。博茨瓦纳目前拥有 艾滋病毒感染率在世界成人中排名第二（25%），但也是艾滋病毒感染率最高的国家。 艾滋病患者接受抗逆转录病毒药物治疗（据世卫组织统计，约90%）。政府 博茨瓦纳、哈佛的培训教师以及必和必拓的主要合作者现在决定将重点放在 努力开展预防研究。基于预防干预措施组合的新研究补助金 包括14名哈佛培训教师中的10名。 为学员提供与艾滋病有关的课程、研讨会和讲习班。我们已经申请了2笔资金 每年有3个博士后岗位。我们估计，我们将培训约18名学员， 年，允许每个博士候选人和一些博士后研究员多年，并假设 几名短期受训人员可以填补一个年度培训名额。津贴将根据目前的程度 和研究经验;因此，在MS或博士课程的MD将有资格获得博士后水平 津贴。所有受训人员都至少有一个理学士学位。我们估计，大约一半将是医生， 临床经验。有些人将是博士后研究员，他们拥有相关领域的博士学位，但没有相关经验。 艾滋病研究。每个学员将有一个主要顾问和一个教师咨询委员会。选择 学员是基于以前的学术表现，参考，经验，并保证， 候选人将返回博茨瓦纳参加艾滋病研究。该计划的质量将受到监督 由来自美国和发展中国家的专家组成的培训咨询委员会。的 培训计划的成功与否将取决于必和必拓高级研究职位的相对增加， 卫生部是指在第二年和第四年后接受该方案培训的个人。成功也将 从成功实施有受训人员参与的预防研究方案来判断， 受训人员在影响力大的期刊上发表文章的数量，以及前受训人员在必和必拓担任的工作人员职位的数量 和卫生部。

PROJECT ABSTRACT The focus for this proposal is on prevention research in Botswana to reduce incidence of HIV/AIDS. This is central to the current research activities of the faculty mentors, who collaborate extensively with each other and with key partners at the Botswana site. Our partner for training is the Botswana Harvard AIDS Institute Partnership (BHP), a limited liability nonprofit corporation (LLC) with the Ministry of Health (MOH) in Botswana. The BHP is the largest HIV/AIDS research organization in Botswana, and one of the largest in Africa. The long- term goals and objectives of this training program are to train research leaders who can take responsibility for the BHP within the next 5-10 years, and to staff the MOH with local AIDS experts. Botswana currently has the second-highest prevalence of HIV in the world for adults (25%), but has also had the highest rate of antiretroviral drug treatment (ART) for patients with AIDS (about 90%, according to WHO). The government of Botswana, the training faculty at Harvard, and the key collaborators at BHP have now decided to focus their efforts on prevention research. A new research grant based on a combination of prevention interventions includes participation by 10 of the 14 Harvard training faculty. AIDS-related courses, seminars, and workshops are available for trainees. We have requested funds for 2 predoctoral and 3 postdoctoral positions each year. We estimate that we will train about 18 trainees over 5 years, allowing for multiple years for each PhD candidate and some postdoctoral fellows, and assuming several short-term trainees could fill a single annual training slot. Stipends will be based on current degrees and research experience; thus an MD on an MS or PhD program would be eligible for a postdoctoral-level stipend. All trainees would have at least a BSc degree. We estimate that about half will be physicians with clinical experience. Some will be postdoctoral fellows who have PhD's in a related area but no experience in AIDS research. Each trainee will have a principal advisor and a faculty advisory committee. Selection of trainees is based on previous academic performance, references, experience, and assurance that the candidates will return to participate in AIDS research in Botswana. The quality of the program will be monitored by a Training Advisory Committee composed of experts from the US and from developing countries. The success of the training program will be judged by the relative increase in senior research positions at BHP and MOH that are individuals who were trained by this program after the second and fourth years. Success will also be judged by the implementation of successful prevention research programs that involve trainees, numbers of trainee publications in high-impact journals, and number of staff positions filled by former trainees at the BHP and the Ministry of Health.