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中文摘要
翻译
描述(由申请者提供):2013年戈登心律失常机制研究会议(GRC)将重点关注基础和翻译科学与临床相关主题的结合。这是第六次GRC关于心律失常机制的研究。自2003年以来,每两年举行一次国际会议,就心律失常和致命性心律失常的潜在机制以及治疗和预防的新方法提供一个科学讨论的场所。这次会议吸引了国内外研究生、博士后研究员和在学术界或工业界工作的高级教员的广泛参与,他们在抗击心律失常和心脏性猝死方面有着共同的利益。我们推测,在心律失常的诊断、治疗和预防方面,迫切需要的进展可能会通过综合方法来发展,这些领域包括遗传学、蛋白质组学和高级信息学、分子和结构生物学、干细胞生物学、蛋白质化学、生物物理学、波传播理论、映射、成像、计算机模拟和非线性动力学。因此,在我们寻求实现共同目标的过程中,沟通是整合这些潜在的不同信息的关键。在举办这次会议时,我们寻求:“为基础和临床科学家之间的面对面对话提供一个论坛。我们认为,这对于确定关键领域是至关重要的,可以从工作台转移到床边。GRC是思想汇聚的理想场所,可以在重点关注的心律失常机制领域形成跨越基础到临床差距的新桥梁。”将拥有不同领域专业知识的科学家聚集在一起,但他们专注于共同的目标。我们认为,正如想法是关键一样,接触新的最先进的方法也是关键。这个GRC汇集了应用各种高度复杂的方法的研究人员,他们有一个共同的目的:更好地了解心律失常疾病的机制,并改进对心律失常疾病患者的诊断、治疗和风险分层。为该领域目前的领导者和未来的领导者之间的网络交流提供了基础。我们建议,心律失常研究的未来取决于新一代。在早期阶段建立网络促进开放和持久的合作,这是发现的关键。GRC会议创造了这样的环境,未来的领导者与当前的领导者和他们的同行建立联系,以建立知识的基础 支持未来几年的心律失常研究。
英文摘要
DESCRIPTION (provided by applicant): The 2013 Gordon Research Conference (GRC) on Cardiac Arrhythmia Mechanisms will focus on integrating basic and translational science with clinically relevant topics. This is the 6th GRC on Cardiac Arrhythmia Mechanisms. Every two years since 2003, this international meeting has provided a venue for scientific discourse on the mechanisms that underlie disturbances in cardiac rhythm and lethal arrhythmias, and the novel approaches to therapy and prevention. The meeting draws broad participation from the national and international communities of graduate students, postdoctoral fellows and senior faculty, working in academia or in industry, which share a common interest in the fight against cardiac arrhythmias and sudden cardiac death. We postulate that urgently needed advances in the diagnosis, treatment and prevention of cardiac arrhythmias are likely to develop through an integrative approach, drawing from various fields such as genetics, proteomics and advanced informatics, molecular and structural biology, stem cell biology, protein chemistry, biophysics, theory of wave propagation, mapping, imaging, computer modeling and nonlinear dynamics. Communication is therefore key in the integration of such potentially disparate information, as we seek to achieve a common goal. In conducting this conference, we seek to: "Provide a forum for face-to-face dialog between basic and clinical scientists. We propose that this is crucial for identification of key areas ripe for translation from bench to bedside. The GRC is an ideal venue for the meeting of the minds that can form new bridges across the basic-to-clinic gap in the focused area of cardiac arrhythmia mechanisms. "Bring together scientists with expertise in disparate fields and yet, focused in a common objective. We propose that, as ideas are critical, so is the exposure to novel state-of-the-art methodologies. This GRC brings together investigators that apply a variety of highly sophisticated methods for one common purpose: to better understand the mechanisms, and improve the diagnosis, treatment and risk stratification of patients with arrhythmia disease. "Provide the fabric for networking between current leaders in the field, and those that will lead in the future. We propose that the future of research in cardiac arrhythmias rests on the new generation. Networking at an early stage fosters open and long lasting collaborations, key to discovery. GRC conferences create the setting, where future leaders link with current ones and with their peers, to build the foundation of knowledge that will support arrhythmia research in the years to come.
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会议论文
Molecular Atlas of the Cardiac Intercalated Disc
Molecular Atlas of the Cardiac Intercalated Disc
Role of PKP2 in epicardial structure and function
Role of desmosomes in cardiac electrical function
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: