Research Career Development in Child Health

我们的儿童健康研究职业发展奖励计划的目标是促进研究 在儿童健康和刺激新的研究举措和职业发展的初级儿科 对儿童疾病感兴趣的研究者。我们的计划支持研究职业发展 最近完成亚专业培训并正在追求基础职业的儿科医生， 与儿童健康相关的转化和/或临床研究。它包括教学和研究部分 提供包括肺病在内的许多儿童疾病的发病机制和演变方面的培训 与早产、囊性纤维化、哮喘、肺炎、败血症、癌症、凝血障碍、骨 骨髓移植、糖尿病、肥胖和心血管疾病、病毒和细菌引起的疾病 病原体和其他折磨儿科人群的疾病。这些疾病背后的过程 包括急性和慢性炎症、先天和特异性免疫、癌细胞生物学、干细胞生物学 和氧化应激。解决这些问题的技术和方法包括基因组学， 蛋白质组学、代谢组学、生物成像、细胞和分子生物学、生物信息学、体内方法 包括突变小鼠技术和流行病学。教学阶段包括研究生培训- 免疫生物学，流行病学和生物统计学以及其他与学者相关的主题的水平课程 兴趣，生物技术培训，包括基因组学和蛋白质组学，生物成像，科学写作和 口头报告一个关键的组成部分是导师在实验室的指导研究经验 和共同导师学者们将作为他们选定的研究项目的正式成员参加， 与该计划的其他成员和共同导师根据其项目的需要。随着时间的推移， 自己的研究计划和方向将从这个培育环境中成长。44名教师导师，27名 来自儿科系的10个部门，领导杰出的，国家认可的研究 项目，他们与癌症，免疫生物学， 感染和代谢综合征。目标是：1）提供出色的培训， 合作的多学科研究，以准备我们的学者成功的职业生涯作为独立的 研究人员追求儿童疾病的重要问题，2）开发新的研究人员， 生物医学研究的未来所需的必要能力和专业知识的广度，3）提供 优秀的导师和共同导师，4）招募和留住我们训练有素的新调查员， 科学的劳动力队伍，并确保劳动力队伍中的多样性得到充分代表， 5)提供能够从事基础研究的合格医生科学家的持续流动 研究疾病过程，并在基础和临床领域之间自由翻译发现。

The objectives of our Child Health Research Career Development Award Program are to advance research in child health and to stimulate novel research initiatives and career development for junior pediatric investigators interested in diseases of childhood. Our Program supports research career development of pediatricians who have recently completed subspecialty training and who are pursuing careers in basic, translational and/or clinical research relevant to child health. It includes didactic and research components to provide training in the pathogenesis and evolution of numerous childhood diseases, including lung disease associated with prematurity, cystic fibrosis, asthma, pneumonia, sepsis, cancer, coagulation disorders, bone marrow transplantation, diabetes, obesity and cardiovascular disease, diseases caused by viral and bacterial pathogens, and other illnesses that afflict the pediatric population. The processes underlying these diseases include acute and chronic inflammation, innate and specific immunity, cancer cell biology, stem cell biology, and oxidative stress. The technologies and methodologies to address these questions include genomics, proteomics, metabolomics, bioimaging, cell and molecular biology, bioinformatics, in vivo approaches including mutant mouse technologies, and epidemiology. A didactic phase includes training in graduate- level courses in immunobiology, epidemiology and biostatistics and other topics relevant to a scholar's interests, training in biotechnologies including genomics and proteomics, bioimaging, scientific writing and oral presentation. A critical component is the mentored research experience in the laboratories of mentors and co-mentors. The scholars will participate as full members of their selected research program, interacting with the other members of the program and with co-mentors as required for their projects. Over time, their own research programs and directions will grow from this nurturing environment. The 44 faculty mentors, 27 from 10 divisions within the Department of Pediatrics, lead outstanding, nationally recognized research programs, and they interact with many colleagues in the rich communities in cancer, immunobiology, infection, and metabolic syndrome at CWRU. The goals are 1) to provide outstanding training in collaborative multi-disciplinary research to prepare our Scholars for successful careers as independent investigators pursuing important questions in childhood diseases, 2) to develop new investigators with the necessary competencies and breadth of expertise needed for the future of biomedical research, 3) to provide excellent mentor- and co-mentorship, 4) to recruit and retain our well-trained new investigators in the scientific workforce and to ensure adequate representation of diversity among people in that workforce, and 5) to provide a continuing flow of qualified physician scientists well able to pursue basic research investigating disease processes and to translate findings freely between the basic and clinical spheres.