Apollo: Increasing Access and Use of Epidemic Models Through the Development and

描述（由申请人提供）：拟议工作的广泛目标是使流行病模型随时可供卫生机构使用，并易于使用，因为是当地电视台的天气模型。该项目将标准化流行病建模中使用的词汇和语法。通过标准化流行病模型所需的许多参数来表示疾病传播，人口的健康状况，疾病传播和疾病控制措施，该项目将减少开发流行病模型所需的时间和精力，并使这些模型的科学和临床用户更容易使用。 具体目标是（1）使用名为Prot <$g <$的工具为流行病建模领域开发标准词汇表;（2）创建项目所需的Prot <$g <$的两个扩展;（3）使用词汇表开发标准语法来表示输入（例如，疾病控制措施）和流行病模型的输出，并在一个名为阿波罗网络服务的现有系统中使用这种语法，使其他计算机程序能够访问流行病模型;（4）增加在超级计算机上运行流行病模型的能力，以证明前三个目标的工作价值。 该项目将与MIDAS研究网络的流行病建模人员合作，开发标准词汇和语法。它将使用扩展的Prot <$g <$软件开发标准词汇表作为本体，这是对象及其相互关系的正式表示。它将使用XML语言表示语法。对流行病模型当前使用的输入和输出数据的分析将推动语法的设计。 这项研究的预期影响是，负责应对流行病的州和联邦官员将经常毫不费力地将流行病模型的预测纳入他们的决策，从而显着增加流行病建模科学对社会的价值。

DESCRIPTION (provided by applicant): The broad aim of the proposed work is to make epidemic models as readily available to health agencies, and as easy-to-use as are weather models for local TV stations. The project will standardize the vocabulary and syntax used in epidemic modeling. By standardizing the many parameters that epidemic models require to represent disease transmission, the health status of a population, disease transmission, and disease control measures, the project will decrease the time and effort required to develop epidemic models and will make them more available to scientific and clinical users of these models. The specific aims are to (1) develop a standard vocabulary for the field of epidemic modeling using a tool called Prot¿g¿; (2) create two extensions to Prot¿g¿ that are needed by the project; (3) develop a standard syntax using the vocabulary for representing the inputs (e.g., disease control measures) and outputs of epidemic models and to use this syntax in an existing system called the Apollo Web Service that makes it possible for other computer programs to access epidemic models; and (4) to increase the capacity to run epidemic models on supercomputers so as to demonstrate the value of the work of the first three aims. The project will work with epidemic modelers from the MIDAS research network to develop the standard vocabulary and syntax. It will use the extended Prot¿g¿ software to develop the standard vocabulary as an ontology, which is a formal representation of objects and their interrelations. It will represent syntax using the XML language. An analysis of the input and output data currently used by epidemic models will drive the design of the syntax. The expected impact of the proposed research is that state and federal officials with responsibility t respond to epidemics will routinely and effortlessly incorporate the predictions of epidemic models into their decision making, thereby increasing significantly the value of the science of epidemic modeling to society.