Sequencing Treatments for Mothers with ADHD & Their At-Risk Children: A SMART pil

描述(由申请人提供)：由于遗传和家庭环境的原因，患有注意力缺陷/多动障碍(ADHD)的母亲的年幼子女患ADHD的风险更高。母亲的ADHD与父母的不良适应和对循证的父母行为训练干预的反应减弱有关。关于如何最好地治疗母亲患有多动症和儿童处于危险之中的家庭，仍然存在许多问题。在这一R34应用中，我们提出了序贯多评估随机试验(SMART)试点，以论证可行性，制定招募、评估、治疗方案，并测试首先使用刺激性药物或行为父母培训治疗母亲，然后根据反应调整治疗的概念，为R01应用做准备。

DESCRIPTION (provided by applicant): Young children of mothers with Attention-Deficit/Hyperactivity Disorder (ADHD) are at heightened risk for ADHD by virtue of genetics and family environment. Maternal ADHD is associated with maladaptive parenting and a diminished response to evidence-based behavioral parent training interventions. Many questions remain with regard to how best to treat families in which the mother has ADHD and child is at risk. In this R34 application, we propose a Sequential Multiple Assessment Randomized Trial (SMART) pilot, to demonstrate feasibility, develop recruitment, assessment, treatment protocols, and test the concept of treating mothers first using either stimulant medication or behavioral parent training, and then adapting treatment based upon response in preparation for the R01 application.