Planning a Strategic HIV Population Science Training Grant in Peru

描述（由申请人提供）：秘鲁受到集中的艾滋病毒流行的影响，其中男男性行为者（MSM）和变性妇女（TW）受影响最大。在过去九年中，秘鲁从全球基金的四轮融资中获得资金，以支持国家应对这一流行病的工作。这使得公立医院能够提供免费抗逆转录病毒疗法，增加避孕套的分发，并加强社区组织。虽然这些努力成功地增加了获得治疗的机会，降低了与艾滋病毒有关的发病率和死亡率，但不清楚预防工作在多大程度上产生了积极影响; 事实上，男男性接触者和台湾妇女的艾滋病毒感染率似乎保持稳定。尽管在过去15年里，秘鲁开展了大量以艾滋病毒为重点的研究，但研究主要包括国际关注的临床试验，这些试验并不支持当地的艾滋病毒预防方案。该规划提案旨在制定艾滋病毒人口科学培训方案，加强机构准备赠款申请和管理/监管资助研究的能力。该项目由卡耶塔诺埃雷迪亚大学的健康、性和人类发展部门牵头，并与位于伯克利、洛杉矶和旧金山弗朗西斯科的加州大学合作。拟议培训的主要领域是：流行病监测、风险和脆弱性的心理社会和结构决定因素研究;综合（生物医学、行为、结构）预防的实施研究;以及旨在了解和改进艾滋病毒决策证据使用情况的政策研究。这一培训方案被认为是与秘鲁的法律和人道主义保护大学和其他机构正在进行或计划进行的其他培训活动相互配合和补充的。

DESCRIPTION (provided by applicant): Peru is affected by a concentrated HIV epidemic, in which men who have sex with men (MSM) and transgender women (TW) are most affected. For the past nine years, Peru has received funding from four Global Fund financing rounds to support the national response to the epidemic. This allowed the introduction of free ART in public hospitals, increased condom distribution, and strengthened community organizations. While these efforts succeeded in increasing access to treatment and reducing HIV related morbidity and mortality, it is unclear to what extent prevention work has had a positive impact; in fact, HIV incidence among MSM and TW seems to have remained stable. Despite substantial HIV-focused research in Peru over the past 15 years, research has mainly consisted of clinical trials of international interest that have not supported local HIV prevention programs. This planning proposal seeks to develop a training program in HIV population science and strengthen institutional capacities to prepare grant applications and manage/regulate funded studies. It is led by the Unit of Health, Sexuality and Human Development at Cayetano Heredia University (UPCH) in collaboration with the Universities of California at Berkeley, Los Angeles and San Francisco. The main areas for this proposed training are: epidemiological surveillance, studies of psychosocial and structural determinants of risk and vulnerability; implementation studies of combination (biomedical, behavioral, structural) prevention; and policy studies oriented to understand and improve the use of evidence for HIV policy making. This training program is conceived as synergistic and complementary with other training initiatives ongoing or planned at UPCH and other institutions in Peru.