Adolescent Medicine Trials Network for HIV/AIDS Interventions

洛杉矶儿童医院（CHLA）的使命是“促进儿童的健康和福祉 通过整合医疗保健，预防服务，医学教育和研究， 回应我们社区的需求，并在爱，同情和尊重人的氛围中。" 自20世纪80年代初以来，CHLA的青少年医学部一直专注于降低以下风险： 通过与联合国建立伙伴关系建立的创新服务、研究和培训模式， 社区通过这些方案，该司提供保健、心理健康、病例管理， 健康教育和药物滥用治疗服务，每年超过9000名青年，并参与 社区一级预防怀孕、艾滋病毒和暴力的干预措施。 自青少年审判网络（ATM）成立以来，CHLA已成为一个 生产性青少年医学试验股（ATU），有助于ATU在 招募和保留临床试验中的受试者，并产生高质量的数据。领域的 在行为试验中，CHLA的参与率和招募率远远高于任何其他ATM站点。为社区 预防试验（连接保护），CHLA是第一个三个（十五）网站完成索引之一 访谈并开始简短的基于场地的调查。至于治疗试验，CHLA一直在 第三是招聘。我们的网站管理质量反映在一贯的积极评价 每半年一次的实地考察 洛杉矶ATU不仅建立了自己作为一个生产ATU，但作出了贡献， ATM通过积极参与委员会和新的行为协议的发展。现场 PI在本项目的所有五年中一直担任ATU主席，并在执行和现场性能方面提供服务。 委员会。此外，CHLA是少数几个ATU站点之一，已经启动了ATN协议（ATN 039）。 CHLA目前正在制定另一项涉及使用手机的原始协议 作为提醒，以解决不遵守。 洛杉矶儿童医院（CHLA）， 青少年医学有必要的经验，专业知识和基础设施，作为一个网站参与， ATN。我们的核心人员配置计划将使我们能够继续有效地招聘和留住员工， 治疗行为和社区试验此外，我们经验丰富的员工将继续积极参与 新协议的开发，从而使我们能够继续为ATN的科学议程做出贡献。 ATN研究议程与公共卫生特别相关，因为它将大大有助于我们的 对青少年艾滋病的认识。

The mission of Childrens Hospital Los Angeles (CHLA) is "to advance the health and well-being of children and adolescents by integrating medical care, preventive services, medical education, and research in response to the needs of our community and in an atmosphere of love, compassion, and respect for people." Since the early 1980's, the Division of Adolescent Medicine at CHLA has focused on reducing risks for young people through innovative models of service, research and training established in partnership with the community. Through these programs, the Division provides health care, mental health, case management, health education, and substance abuse treatment services to over 9000 youth annually, and is involved in community-level interventions for pregnancy, HIV, and violence prevention. Since the inception of the Adolescent Trials Network (ATM), CHLA has established itself as a productive Adolescent Medicine Trials Unit (ATU), contributing to the primary mission of the ATUs in the recruitment and retention of subjects in clinical trials and production of high quality data. In the area of behavioral trials, CHLA has far greater participation and recruitment than any other ATM site. For community prevention trials (Connect to Protect¿), CHLA is one of the first three (of fifteen) sites to complete the index interviews and begin the brief venue based surveys. As for therapeutic trials, CHLA has consistently been in the top third for recruitment. The quality of our site management is reflected in consistently positive reviews at our semi-annual site visits. The Los Angeles ATU has not only established itself as a productive ATU, but has contributed to the ATM through active involvement in committees and the development of new behavioral protocols. The site PI has been the ATU chair for all five years of this project and served on the Executive and Site performance committees. In addition, CHLA is one of the few ATU sites to have initiated an ATN protocol (ATN 039). CHLA is currently in the process of developing yet another original protocol involving the use of cell phones as reminders to address non-adherence. The following application documents that Childrens Hospital Los Angeles (CHLA), Division of Adolescent Medicine has the experience, expertise and infrastructure necessary to participate as a site in the ATN. Our core staffing plans will allow us to continue effective recruitment and retention into therapeutic, behavioral and community trials. In addition our experienced staff will continue to be active in the development of new protocols and thus allow us to continue to contribute to the ATN scientific agenda. The ATN research agenda is of particular relevance to public health, as it will significantly contribute to our understanding of HIV in adolescents.