Tulane National Primate Research Center

描述（由申请人提供）：本申请为杜兰国家灵长类动物研究中心（TNPRC）申请资助，为期五年，从2013年5月1日到2018年4月30日。资金将用于支持中心的管理、运营、兽医资源、科研资源、试点研究计划、改进和现代化、外联以及教育和培训活动。近三十年来，TNPRC研究项目的主要重点一直是传染病。此外，再生医学项目已经开发，这是密切联系在杜兰干细胞研究和再生医学中心。目前，传染病项目的主要资助领域是艾滋病、莱姆病、结核病和与生物防御相关的病原体。这些是多学科研究，涉及TNPRC几个部门的研究人员和中心以外的合作者。这些研究的共同点是关注疾病的发病机制，并利用这些发现为疫苗、诊断和治疗方法的开发提供信息。再生医学项目为多种疾病的治疗提供了新的方法，为我们的研究项目提供了多样性，并提供了与大学其他部门的重要联系。自2007年5月底最后一次提交TNPRC基础赠款以来，该中心经历了重大的增长和变化。个人研究人员发起的奖励资金增加了一倍，三座新建筑已经建成，其中一座是区域生物安全实验室；一个大型生物安全三级设施。TNPRC是唯一拥有区域生物安全实验室的NPRC。我们还扩大了南校区，以允许非人灵长类动物繁殖群体的未来增长。

DESCRIPTION (provided by applicant): This application requests funding for the Tulane National Primate Research Center (TNPRC) for the five year period beginning May 1, 2013 through April 30, 2018. Funds will be used to support the administration, operations, veterinary resources, scientific research resources, pilot research program, improvements and modernization, outreach, and education and training activities of the Center. For nearly three decades, the main focus of the TNPRC research program has been infectious diseases. In addition, a program in regenerative medicine has developed, which Is closely linked to the Center for Stem Cell Research and Regenerative Medicine at Tulane. The major agent-specific areas of funding for the infectious diseases program are currently AIDS, Lyme disease, tuberculosis and biodefense-related agents. These are multidisciplinary studies involving investigators in several Divisions at the TNPRC and collaborators outside the Center. Common to these studies is a focus on disease pathogenesis and on using such findings to inform the development of vaccines, diagnostics and therapeutics. The regenerative medicine program allows novel approaches to the treatment of many types of disease, provides diversity to our research program, and provides an important link to the rest of the university. The period since the last submission of the TNPRC base grant, at the end of May 2007, has been a time of significant growth and change at the Center. Individual investigator-Initiated award funding has doubled and three new buildings have been completed, one of which is a Regional Biosafety Laboratory; a large biosafety level 3 facility. The TNPRC is the only NPRC to have a Regional Biosafety Laboratory. We have also expanded our South Campus to allow future growth of the nonhuman primate breeding colony. Based on the progress in the funding period, we are optimistic about the future. Strengths on which we can capitalize Include unique resources and capabilities In research areas that match NIH and national priorities, faculty appointments, strong and diverse research resources, a talented and dedicated staff, excellent interactions and collaborations with area universities and an outstanding relationship with our host institution and state and federal legislators.