Interdisciplinary Training in Genes and the Environment

描述(由申请人提供) 哈佛大学公共卫生学院(HSPH)的基因与环境跨学科培训计划满足了对训练有素的科学家的迫切需求，这些科学家了解并致力于分子和环境暴露生物学交叉领域的尖端研究，并在统计和计算方法方面进行了强有力的培训。培训计划的基础是19名有成就和经验的多学科教员的积极参与，其中包括环境健康科学家、分子生物学家、分子流行病学家和计算生物学家。拟议培训方案的两个相互关联的目标是： *培训真正的合作伙伴，使其能够从事方法学研究，这些研究的动机是人类环境暴露和复杂疾病的遗传易感性研究中出现的困难分析问题，并有助于解决这些问题。 *鼓励跨学科研究，特别是在遗传学和各种“组学”方面的研究，这些“组学”是在实验室和人口科学中确定与环境暴露有关的生物活动的新方法所产生的。 博士前学生将获得公共卫生(BPH)生物科学博士学位，在最近的NRC分析中，该公共卫生博士项目排名全国第一。博士学位是通过哈佛大学文理研究生院授予的。博士后研究员将由两名HSPH教师指导，以支持和鼓励跨学科培训。该计划建议继续支持8名博士后学生，并寻求每年增加1名博士后研究员，每年总共增加2名博士后研究员。这些博士后实习生将拥有与暴露生物学/环境卫生科学或基因组学/蛋白质组学计算领域相关的高级学位(博士、医学博士、医学博士/博士学位)，并将对交叉培训研究经验特别感兴趣。基因与环境跨学科培训项目的所有受训人员将获得一个在基因组学、环境健康科学和定量方法方面获得同等技能的绝佳机会，以便在人类基因与环境的跨学科研究中发挥领导作用，最终目标是在制定有效的疾病预防和干预策略方面服务于公共卫生利益。

DESCRIPTION (provided by applicant) The Interdisciplinary Training in Genes and the Environment program at the Harvard School of Public Health (HSPH) meets the critical need for well-trained scientists who have an understanding of, and commitment to, cutting-edge research at the intersection of molecular and environmental exposure biology with strong training in statistical and computational methods. The Training Program is based on active participation by 19 accomplished and experienced multidisciplinary faculty members, including environmental health scientists, molecular biologists, molecular epidemiologists, and computational biologists. The two interrelated goals of the proposed Training Program are: * To train true collaborative partners able to pursue methodological research that is motivated by, and helps to solve, difficult analytic issues that arise in studies of human environmental exposures and genetic susceptibility to complex diseases. * To encourage interdisciplinary research, especially in genetics and the various "omics" arising from new methodologies for characterizing biological activity associated with environmental exposures in laboratory and population sciences. Pre-doctoral students will obtain the Ph.D. in Biological Sciences in Public Health (BPH), the public health doctoral program ranked first in the nation in the recent NRC analysis. The Ph.D. degree is awarded through the Graduate School of Arts and Sciences at Harvard University. Postdoctoral fellows will be mentored by two HSPH faculty to support and encourage cross-disciplinary training. The Program proposes continued support for eight pre-doctoral students and seeks to add one postdoctoral fellow per year for a total of two each year of the award. These postdoctoral trainees will have an advanced degree (Ph.D., M.D., M.D./Ph.D. or other doctoral degree) relevant to exposure biology/environmental health sciences or computational areas of genomics/proteomics and will have specific interest in cross-training research experience. All trainees in the Interdisciplinary Training in Genes and Environment Program will be provided an outstanding opportunity to become equally skilled in genomics, environmental health sciences, and quantitative methods in order to attain leadership roles in interdisciplinary studies of human genes and the environment, with the ultimate goal of serving public health interests in developing effective disease prevention and intervention strategies.