Data Management and Statistical Core

核心C：数据管理和统计摘要 数据管理和统计核心提供统计咨询、数据管理和信息 调拨资源以提高ADRC进行的阿尔茨海默病研究的质量 调查人员。 具体目标是： 1.为核心和项目提供数据库支持。协调进场，质量控制， 门诊招生、评估、随访数据的管理与分析 和由中心临床核心招募的对照受试者。同样，为了协调条目，质量 控制、管理和分析该中心的神经病理核心和 由临床核心中心和合作研究人员生成的神经成像数据。 2.准备ADRC数据库，以便常规提交给国家阿尔茨海默氏症协调中心 (NACC)，支持新的NACC程序和倡议，并解决NACC查询。 3.为发改委调查人员提供统计设计和分析咨询服务。设计 咨询包括电力计算和统计分析规划。数据分析支持范围 从提供简单的描述性统计到进行复杂的多变量统计分析。 4.开发新的统计方法，重点应用于阿尔茨海默病数据。 5.对调查人员、受训人员和初级教员进行统计分析原理和使用的教育 方法论。

CORE C: DATA MANAGEMENT AND STATISTICAL - ABSTRACT The Data Management and Statistical Core provide statistical consulting, data management and information transfer resources to enhance the quality of Alzheimer's disease research conducted by the ADRC investigators. The specific aims are: 1. To provide database support to the Cores and Projects. To coordinate the entry, quality control, management and analysis of data generated by the enrollment, evaluation, and follow up of outpatient and control subjects recruited by the Center's Clinical Core. Similarly, to coordinate the entry, quality control, management and analysis of data generated by the Center's Neuropathology Core and neuroimaging data generated by the Clinical Core and collaborating investigators. 2. To prepare the ADRC database for routine submission to the National Alzheimer's Coordinating Center (NACC), support new NACC procedures and initiatives, and resolve NACC queries. 3. To provide statistical design and analysis consultation services to ADRC investigators. Design consultation includes power calculations and statistical analysis planning. Data analysis support ranges from providing simple descriptive statistics to the conduct of complex multivariate statistical analyses. 4. To develop new statistical methodology focused on application to Alzheimer's disease data. 5. To educate investigators, trainees and junior faculty in the principles and use of statistical analysis methodologies.