Administrative and Protocol Management Core

这笔赠款的行政和礼宾管理核心（核心A）将提供行政支助 为四个科学项目和两个科学核心的计划，题为“替代配方的 替诺福韦和UC 781”。具体而言，行政核心将1）提供行政监督， 该计划的科学项目和核心，2）为该计划提供财政监督和协调 在所有项目和核心，3）是这个研究计划和之间的主要联系点， NIAID项目官员，负责HIV局部杀微生物剂的临床前/临床综合项目， 4)计划和协调科学指导委员会的每月电话会议，5）建立一个 外部科学家科学咨询小组出席科学指导委员会年度会议 委员会和NIAID计划科学家，以及6）协助核心C与研究活动的协调， 合作伙伴和康拉德。此外，该核心还将为 项目3和4的临床研究，并确保CONRAD之间的顺利互动，其中持有 UC 781和替诺福韦的所有权，匹兹堡大学IRB和艾滋病部门。这 核心，这将是由博士沙龙希利尔和丽莎罗汉领导，将支持所有四个科学项目和两个 通过促进与其他研究人员的科学互动和合作， 从事杀微生物剂的研究

The Administrative and Protocol Management Core (Core A) of this grant will provide administrative support for the four scientific projects and two scientific cores for the program entitled, "Alternative Formulations of Tenofovir and UC781". Specifically, the Administrative Core will 1) provide administrative oversight of the scientific projects and cores in this program, 2) provide fiscal oversight and coordination for the program across all projects and cores, 3) be the primary point of contact between this research program and the NIAID Program Officer in charge of the Integrated Preclinical/Clinical Program for HIV Topical Microbicides, 4) plan and coordinate monthly conference calls for the Scientific Steering Committee, 5) establish a Scientific Advisory Panel of outside scientists to attend an annual meeting of the Scientific Steering Committee and NIAID program scientists, and 6) assist Core C with coordination of research activities with corporate partners and CONRAD. In addition, this Core will provide protocol management support for the clinical studies in Projects 3 and 4, and ensure smooth interactions between CONRAD, which holds the proprietary rights to UC781 and tenofovir, the University of Pittsburgh IRB, and the Division of AIDS. This Core, which will be led by Drs. Sharon Hillier and Lisa Rohan, will support all four scientific projects and both scientific cores through the promotion of scientific interactions and collaborations with other investigators engaged in microbicide research.