BIOSTATISTICS SHARED RESOURCE GROUP

生物统计共享资源(BSR)的使命是以经济高效的方式为霍林斯癌症中心(HCC)提供杰出的生物统计领导和支持，并充当促进不同研究人员、其他共享资源和CC内项目之间互动的中心。在Elizabeth Garrett-Mayer博士的领导下，BSR由在癌症研究和肿瘤学方面接受过深入培训的生物统计学家组成，并在这些努力中使用的各种方法方面具有互补的专业知识。Garrett-Mayer博士利用基于团队的方法来实现资源的目标。自2009年CCSG获奖以来，合作的范围证明了CC BSR的成功和有效性，截至2012年底，开发了89项ROI申请和额外的239项其他拨款申请(例如POI、DOD、T32)；提交和/或发表了100多篇与BSR成员共同撰写的手稿；以及开发了48项由研究人员发起的临床研究研究。 BSR的目的是： *为肝细胞癌研究人员在研究设计、数据分析、质量等方面提供统计支持 控制、手稿准备和竞争性拨款提案的开发。 *调整、开发和验证新的统计方法，以应对 正在进行的肝细胞癌研究。 *通过与计划一起参加项目开发会议，促进CC内部的互动 领导者和其他共享资源主管。 *在协议会议定书审查委员会和数据与安全监测委员会任职，以提供 对拟议和正在进行的内部和外部临床试验的关键投入。 *为教职员工、研究员、住院医生和工作人员提供统计方法和方法方面的持续教育 肝细胞癌的。

The mission of the Biostatistics Shared Resource (BSR) is to provide outstanding biostatistics leadership and support in a cost-effective manner for the Hollings Cancer Center (HCC) and to act as a hub that facilitates interactions among the various investigators, other shared resources, and programs within the HCC. Under the leadership of Dr. Elizabeth Garrett-Mayer, the BSR is composed of biostatisticians with in-depth training in cancer research and oncology and complementary expertise in the various approaches used in these endeavors. Dr. Garrett-Mayer utilizes a team-based approach to accomplish the goals of the resource. The success and effectiveness of the HCC BSR are demonstrated by the extent of collaborations since the CCSG was awarded in 2009, resulting in the development of 89 ROI applications and an additional 239 other grant applications {e.g., POI, DOD, T32) through the end of 2012; submission and/or publication of more than 100 manuscripts with BSR members as co-authors; and development of 48 investigator-initiated clinical research studies. The purposes of the BSR are to: * Provide statistical support to HCC investigators for the design of studies, analysis of data, quality control, manuscript preparation, and development of competitive grant proposals. * Adapt, develop, and validate novel statistical methodologies to address emerging approaches in ongoing HCC research. * Facilitate interactions within the HCC by participating in project development meetings with program leaders and other shared resource directors. * Serving on the HCC Protocol Review Committee and Data & Safety Monitoring Committee to provide critical input into proposed and ongoing internal and external clinical trials. * Provide ongoing education in statistical methods and approaches for faculty, fellows, residents and staff of the HCC.