Development and Investigation of Assays For Cardiovascular Risk Assessment
Development and Investigation of Assays For Cardiovascular Risk Assessment
批准号:
8952837
负责人:
Alan Thomas Remaley
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
Apolipoproteins BBiological AssayCholesterolClinical InvestigatorCoronary ArteriosclerosisDevelopmentEffectivenessEnzymesGroupingInvestigationLipoproteinsMeasuresMeta-AnalysisMethodsPatientsPerformancePublishingRisk AssessmentRisk EstimateSignal TransductionTechniquesTestingbasecardiovascular risk factordiagnostic accuracyimprovedlipoprotein lipaseresponse
中文摘要
在过去的一年里,我们评估并实现了一种新的方法来测量脂蛋白减去和大小的核磁共振。该测试现已通过CRIS提供给其他临床研究人员使用。使用各种聚类技术,我们正在研究基于其脂蛋白谱的患者分组,如核磁共振测量,心血管风险。我们还在研究添加外源性脂蛋白修饰酶(如脂蛋白脂肪酶)时核磁共振信号的变化,以确定这是否提供了与心血管风险相关的额外信息。我们还参与了最近发表的一项荟萃分析,比较载脂蛋白ob和核磁共振评估心血管风险。
英文摘要
In the past year, we evaluated and implemented a new method for measuring lipoprotein subtractions and size by NMR. This test is now available through CRIS for other clinical investigators to use. Using a variety of clustering techniques, are investigating the grouping of patients based on their lipoprotein profile, as measured by NMR, with cardiovascular risk. We are also investigating the change in the NMR signal in response to adding exogenous lipoprotein modifying enzymes, such as Lipoprotein Lipase, to determine if this provides additional information related to cardiovascular risk. We also participated in a recently published meta analysis comparing ApoB versus NMR for assessing cardiovascular risk.
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科研奖励(0)
会议论文
Development Of New Assays For Lipoprotein Testing
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批准号:6675216
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development of recombinant Lecithin Cholesterol Acyltransferase as a therapeutic
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批准号:8344887
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项目类别:
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资助金额:$68.86万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Use Of Animal Models To Study Genes That Modulate Atherosclerosis
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批准号:10008759
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项目类别:
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资助金额:$103.09万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development and Diagnostic Use of Rapid Immunoassays
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批准号:6227890
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
lopment And Diagnostic Use Of Rapid Immunoassays
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批准号:6675214
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development Of New Assays For Lipoprotein Testing
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批准号:6825465
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development and Investigation of Assays For Cardiovascular Risk Assessment
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批准号:8565337
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Use Of Animal Models To Study Genes That Modulate Atherosclerosis
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批准号:8939766
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项目类别:
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资助金额:$126.26万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development of Apo Mimetic Peptides for the Treatment Cardiovascular Disease
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批准号:8558035
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项目类别:
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资助金额:$66.32万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Regulation of lipid metabolism by miRNAs
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批准号:8344886
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项目类别:
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资助金额:$103.29万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development of Apo Mimetic Peptides for the Treatment Cardiovascular Disease
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批准号:8158047
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项目类别:
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资助金额:$65.05万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development And Diagnostic Use Of Rapid Immunoassays
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批准号:6543086
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Method Development: Lipoprotein fraction analysis
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批准号:6543087
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Role of fatty acids in health and disease.
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批准号:10929191
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项目类别:
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资助金额:$150.35万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Regulation of lipid metabolism by miRNAs
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批准号:8158043
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项目类别:
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资助金额:$97.58万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Use Of Animal Models To Study Genes That Modulate Atherosclerosis
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批准号:8158019
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项目类别:
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资助金额:$97.58万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Use Of Animal Models To Study Genes That Modulate Atherosclerosis
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批准号:8344759
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项目类别:
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资助金额:$105.79万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development of recombinant Lecithin Cholesterol Acyltransferase as a therapeutic
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批准号:8558032
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项目类别:
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资助金额:$66.32万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development of Apo Mimetic Peptides for the Treatment Cardiovascular Disease
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批准号:8746660
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项目类别:
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资助金额:$106.54万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
Development of recombinant Lecithin Cholesterol Acyltransferase as a therapeutic
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批准号:8746657
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项目类别:
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资助金额:$106.54万
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财政年份:--
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负责人:Alan Thomas Remaley
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依托单位:
海外基金