Tulane National Primate Research Center

描述（由申请人提供）：本申请要求资助杜兰国家灵长类动物研究中心（TNPRC）从2013年5月1日开始至2018年4月30日的五年期。资金将用于支持该中心的管理、运营、兽医资源、科研资源、试点研究计划、改进和现代化、推广以及教育和培训活动。近三十年来，TNPRC研究计划的主要重点一直是传染病。此外，还开发了一个再生医学项目，该项目与杜兰大学的干细胞研究和再生医学中心密切相关.目前，传染病方案的主要特定药物领域是艾滋病、莱姆病、结核病和生物防御相关药物。这些是多学科研究，涉及TNPRC几个部门的研究人员和中心外的合作者。这些研究的共同点是关注疾病的发病机制，并利用这些发现为疫苗、诊断和治疗的开发提供信息。再生医学计划允许新的方法来治疗许多类型的疾病，为我们的研究计划提供多样性，并提供了一个重要的链接到大学的其他部分。自上次于2007年5月底提交TNPRC基本赠款以来，该中心经历了显著的增长和变化。由单个制造商发起的奖励资金增加了一倍，三座新建筑已经完工，其中一座是区域生物安全实验室，这是一个大型生物安全三级设施。该中心是唯一拥有区域生物安全实验室的NPRC。我们还扩大了我们的南校区，以允许非人类灵长类繁殖殖民地的未来增长。 基于融资期的进展，我们对未来持乐观态度。我们可以利用的优势包括独特的资源和能力，在研究领域，符合NIH和国家的优先事项，教师任命，强大和多样化的研究资源，有才华和敬业的工作人员，良好的互动和与地区大学的合作，并与我们的主办机构和州和联邦立法者的杰出关系。

DESCRIPTION (provided by applicant): This application requests funding for the Tulane National Primate Research Center (TNPRC) for the five year period beginning May 1, 2013 through April 30, 2018. Funds will be used to support the administration, operations, veterinary resources, scientific research resources, pilot research program, improvements and modernization, outreach, and education and training activities of the Center. For nearly three decades, the main focus of the TNPRC research program has been infectious diseases. In addition, a program in regenerative medicine has developed, which Is closely linked to the Center for Stem Cell Research and Regenerative Medicine at Tulane. The major agent-specific areas of funding for the infectious diseases program are currently AIDS, Lyme disease, tuberculosis and biodefense-related agents. These are multidisciplinary studies involving investigators in several Divisions at the TNPRC and collaborators outside the Center. Common to these studies is a focus on disease pathogenesis and on using such findings to inform the development of vaccines, diagnostics and therapeutics. The regenerative medicine program allows novel approaches to the treatment of many types of disease, provides diversity to our research program, and provides an important link to the rest of the university. The period since the last submission of the TNPRC base grant, at the end of May 2007, has been a time of significant growth and change at the Center. Individual investigator-Initiated award funding has doubled and three new buildings have been completed, one of which is a Regional Biosafety Laboratory; a large biosafety level 3 facility. The TNPRC is the only NPRC to have a Regional Biosafety Laboratory. We have also expanded our South Campus to allow future growth of the nonhuman primate breeding colony. Based on the progress in the funding period, we are optimistic about the future. Strengths on which we can capitalize Include unique resources and capabilities In research areas that match NIH and national priorities, faculty appointments, strong and diverse research resources, a talented and dedicated staff, excellent interactions and collaborations with area universities and an outstanding relationship with our host institution and state and federal legislators.