A.S.P.E.N. 2015 RW Taste Signaling: Impact on Food Selection, Intake, and Health

描述（由申请方提供）：美国肠外肠内营养学会（A.S.P.E.N.） 研究研讨会（RW）是一个非常成功和科学上受人尊敬的会议，汇集了营养研究人员和临床医生，致力于发展循证临床实践，确保尖端的患者护理。 A.S.P.E.N.的目标2015 RW“Taste Signaling： 对食物选择、摄入和健康的影响”是传播与食物的味道特性和需要状态、摄食后事件和食物消费行为之间的相互作用有关的新发现，以及这些相互作用对整个生命周期的营养和健康的影响。 早期生活经历对味觉相关行为的影响， 以及胃旁路手术对肠道肽，口味偏好，食物选择的影响也将被探讨。 美国体育协会 2015年RW是及时和新颖的：我将提供一个强大的场所，为早期职业生涯中的跨学科合作，建立临床医生和研究人员从基础到应用环境谁分享味觉信号和食物选择之间的相互作用的兴趣，摄入量，和健康。该RW特别符合NIDDK关于信号和营养感测的科学计划，对预防和管理肥胖具有重要意义。 也是 与A.S.P.E.N.相关的主题 研究人员和临床医生，因为更好地了解这些相互作用可能对有肥胖风险或被诊断患有肥胖的个体的临床护理和结果产生潜在影响。 2015年A.S.P.E.N.的目标RW方案是：1）吸引不同的科学家，演讲者和与会者，他们对整个胃肠道味觉受体的信号传导机制有共同的兴趣，可以影响整个生命周期的食物摄入和营养代谢，生理学和健康，从而将临床营养和代谢研究从实验室连接到床边; 2）通过促进跨学科研究人员（从基础科学家到临床试验人员）与能够 应用他们的研究结果，以改善个人谁是在风险或被诊断为肥胖症的护理; 3）提供机会，指导有兴趣在工作的接口的味觉信号生物学和临床营养的健康和疾病的早期职业研究人员; 4）在临床和基础科学环境中促进开发赠款申请，以测试肥胖症的新疗法; 5）向更广泛的科学界传播2015年RW活动和信息。 2015年关于味觉信号与食物选择，摄入量和健康之间相互作用的RW有望在实现本申请中概述的具体目标方面取得巨大成功，方法是建立在先前研讨会的基础上，并提供对推进营养支持和患者护理科学至关重要的多学科场所。

DESCRIPTION (provided by applicant): The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Research Workshop (RW) has been a highly successful and scientifically respected conference that brings together nutrition researchers and clinicians committed to the development of evidence-based clinical practices ensuring cutting-edge patient care. The goal of the A.S.P.E.N. 2015 RW "Taste Signaling: Impact on Food Selection, Intake, and Health" is to disseminate new findings related to the interactios between the taste properties of food and need-state, postingestive events, and food consumption behaviors, and the implications of these interactions on nutrition and health throughout the lifespan. The influence of early life experiences on taste-related behavior, as well as the impact of gastric bypass surgery on gut peptides, taste preferences, an food selection will also be explored. The A.S.P.E.N. 2015 RW is both timely and novel: i will provide a powerful venue for inter-disciplinary collaboration among early career an established clinicians and researchers from basic to applied settings who share interest in the interactions between taste signaling and food selection, intake, and health. This RW is particularly aligned with NIDDK's scientific program on Signaling and Nutrient Sensing with has significant implications for the prevention and management of obesity. It is also topic of key relevance to A.S.P.E.N. researchers and clinicians because of the potentia impact that a better understanding of these interactions might have on clinical care ad outcomes in individuals at risk for or who are diagnosed with obesity. The aims of the 2015 A.S.P.E.N. RW program are: 1) to attract a diverse group of scientists, speakers and attendees with common interest in mechanisms by which signaling by taste receptors throughout the GI tract can influence food intake and nutrient metabolism, physiology, and health throughout the lifespan, thus bridging clinical nutrition and metabolic research from bench to bed-side; 2) to support translational science by fostering communication and collaboration among interdisciplinary researchers (from basic scientists to clinical trialists) with clinicians who can apply their findings to improve the care of individuals who are at risk for or are diagnosed with obesity; 3) to provide opportunities for mentorship of early career researchers interested in working at the interface of taste signaling biology and clinial nutrition in health and disease; 4) to promote development, in both clinical and basic science settings, of grant applications with the aim of testing novel treatments for obesity; 5) to disseminate the 2015 RW activities and information to the broader scientific community. The 2015 RW on the interactions between taste signaling and food selection, intake and health is poised to be highly successful in achieving the specific aims outlined in this application by building on the foundation of prior workshops and providing the multidisciplinary venue that is critical for advancing the science of nutrition support and patient care.